ID A0A0S7X9U5_9DELT Unreviewed; 124 AA.
AC A0A0S7X9U5;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 13-SEP-2023, entry version 24.
DE RecName: Full=diaminopimelate epimerase {ECO:0000256|ARBA:ARBA00013080};
DE EC=5.1.1.7 {ECO:0000256|ARBA:ARBA00013080};
DE Flags: Fragment;
GN ORFNames=AMJ42_02200 {ECO:0000313|EMBL:KPJ59216.1};
OS Deltaproteobacteria bacterium DG_8.
OC Bacteria; Deltaproteobacteria.
OX NCBI_TaxID=1703397 {ECO:0000313|EMBL:KPJ59216.1, ECO:0000313|Proteomes:UP000051875};
RN [1] {ECO:0000313|EMBL:KPJ59216.1, ECO:0000313|Proteomes:UP000051875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG_8 {ECO:0000313|EMBL:KPJ59216.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-
CC diaminoheptanedioate; Xref=Rhea:RHEA:15393, ChEBI:CHEBI:57609,
CC ChEBI:CHEBI:57791; EC=5.1.1.7;
CC Evidence={ECO:0000256|ARBA:ARBA00000599};
CC -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005196}.
CC -!- SIMILARITY: Belongs to the diaminopimelate epimerase family.
CC {ECO:0000256|ARBA:ARBA00010219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPJ59216.1}.
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DR EMBL; LIZV01000048; KPJ59216.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S7X9U5; -.
DR PATRIC; fig|1703397.3.peg.258; -.
DR UniPathway; UPA00034; UER00025.
DR Proteomes; UP000051875; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0008837; F:diaminopimelate epimerase activity; IEA:UniProtKB-EC.
DR GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:UniProtKB-UniPathway.
DR InterPro; IPR018510; DAP_epimerase_AS.
DR InterPro; IPR001653; DAP_epimerase_DapF.
DR NCBIfam; TIGR00652; DapF; 1.
DR PANTHER; PTHR31689:SF0; DIAMINOPIMELATE EPIMERASE; 1.
DR PANTHER; PTHR31689; DIAMINOPIMELATE EPIMERASE, CHLOROPLASTIC; 1.
DR Pfam; PF01678; DAP_epimerase; 1.
DR SUPFAM; SSF54506; Diaminopimelate epimerase-like; 1.
DR PROSITE; PS01326; DAP_EPIMERASE; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154}.
FT ACT_SITE 76
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10125"
FT NON_TER 124
FT /evidence="ECO:0000313|EMBL:KPJ59216.1"
SQ SEQUENCE 124 AA; 13673 MW; 2AECFC5291E9FEEF CRC64;
MKLIPFSKMS AGGNDFIIID NRQNILESQR AKECAQKVCR RKLSIGADGL ILIEDSKKAD
FKWRFFNADG SEAEMCGNGG RCVARLANIK GIASHTLTFE TLAGIIKAEV MGDRVKLQLP
LPFN
//
