ID A0A0S8AXW5_9CHLR Unreviewed; 299 AA.
AC A0A0S8AXW5;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=AMJ56_18125 {ECO:0000313|EMBL:KPK04048.1};
OS Anaerolineae bacterium SG8_19.
OC Bacteria; Chloroflexota; Anaerolineae.
OX NCBI_TaxID=1703386 {ECO:0000313|EMBL:KPK04048.1, ECO:0000313|Proteomes:UP000050892};
RN [1] {ECO:0000313|EMBL:KPK04048.1, ECO:0000313|Proteomes:UP000050892}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8_19 {ECO:0000313|EMBL:KPK04048.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK04048.1}.
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DR EMBL; LJNN01000316; KPK04048.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8AXW5; -.
DR PATRIC; fig|1703386.3.peg.1969; -.
DR Proteomes; UP000050892; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08267; MDR1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR44013; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR PANTHER; PTHR44013:SF1; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 10..294
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 299 AA; 32473 MW; F533A04E65D648FE CRC64;
MKAIVCKKSG PPDVLQLKDL EKPAPKDNEV LVKIHAATVT AGDVILRNLK FPLTIVFGLF
GMPRKEIPGH ELAGEIESVG VEVKLFKEGD QVFGTTTGLR SGSYAEYICL PEEGVLAIKP
ANMTYEEAAA VPIGAMTALQ ILRKGNIQSG QKVLIYGASG SVGTYAVQLA KYFGAEVTGV
CSTTNLEMVK SLGTDKVIDY TKEDFTKSGE SYDVIFDAAG KISSSRSKGS LKQRGTYLSV
KSSTNEKTED LVFLKELIEA GKIRSVIDRR YPLEQIVEAH RYVEKGHKKG NVVITVEHN
//
