ID A0A0S8B8E2_9PROT Unreviewed; 504 AA.
AC A0A0S8B8E2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=AMJ64_05115 {ECO:0000313|EMBL:KPK07925.1};
OS Betaproteobacteria bacterium SG8_39.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1703390 {ECO:0000313|EMBL:KPK07925.1, ECO:0000313|Proteomes:UP000051483};
RN [1] {ECO:0000313|EMBL:KPK07925.1, ECO:0000313|Proteomes:UP000051483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8_39 {ECO:0000313|EMBL:KPK07925.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK07925.1}.
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DR EMBL; LJTQ01000032; KPK07925.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8B8E2; -.
DR STRING; 1703390.AMJ64_05115; -.
DR PATRIC; fig|1703390.3.peg.1586; -.
DR Proteomes; UP000051483; Unassembled WGS sequence.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 26..484
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 504 AA; 53932 MW; 034AE76D8788F2C7 CRC64;
MNKPAELKLD VIPLWIDGRT VTQAARMGDV FNPATGQVIR RVPYADAKTV DAAVQAARRA
LPAWRDTPPL RRSRILQRFL QLMQDQQQDL ARRVSEEHGK TIPDAAGSIQ RGIEVIEFAC
GIPHLLKGEH AENVGTQVDS HSVRQPVGVC VGITPFNFPV MVPLWMFPVA LACGNTFVLK
PSEKDPSASI RMAELLKEAG LPDGVFNVVH GDKAAVDALL THPGVDAVSF VGSTPIAKYI
YETSARLGKR VQALGGAKNH AVVLPDADLE FTADALIGAA YGSAGERCMA VSAVVAVGEA
GDPLVKLLAQ KAKAVKVGPG DREGMDMGAL VTGEHRDKVK GYVDQGVKEG ATAVVDGRGL
KVKGYEDGFY LGTTLFDHVT PQMAVYQNEI FGPVLVVLRA KTLEEAIALV NANPYANGAA
IFTESGGAAR RFANEVSIGM VGVNVPIPVP MAFFSFGGWK SSLFGDLHVH GMEGVKFYTR
TKVITSRWPH QDTPAPGFHM PTMG
//
