ID A0A0S8EW87_9GAMM Unreviewed; 399 AA.
AC A0A0S8EW87;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 13-SEP-2023, entry version 25.
DE RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 2 {ECO:0000256|ARBA:ARBA00014657};
DE EC=2.3.1.179 {ECO:0000256|ARBA:ARBA00012356};
DE AltName: Full=3-oxoacyl-[acyl-carrier-protein] synthase II {ECO:0000256|ARBA:ARBA00032171};
DE AltName: Full=Beta-ketoacyl-ACP synthase II {ECO:0000256|ARBA:ARBA00029675};
GN ORFNames=AMS22_09485 {ECO:0000313|EMBL:KPK52257.1};
OS Thiotrichales bacterium SG8_50.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales.
OX NCBI_TaxID=1703416 {ECO:0000313|EMBL:KPK52257.1, ECO:0000313|Proteomes:UP000051903};
RN [1] {ECO:0000313|EMBL:KPK52257.1, ECO:0000313|Proteomes:UP000051903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG8_50 {ECO:0000313|EMBL:KPK52257.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK52257.1}.
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DR EMBL; LJTW01000115; KPK52257.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8EW87; -.
DR PATRIC; fig|1703416.3.peg.3874; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000051903; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR03150; fabF; 1.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR PIRSF; PIRSF000447; KAS_II; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:KPK52257.1};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:KPK52257.1}.
FT DOMAIN 3..397
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 399 AA; 42100 MW; FBCBEC2FAF696047 CRC64;
MSKRRVAITG LGILSPIGIG VNENWQAIMA GRGGITQITR FDATGYPATI AGEVKNFIPT
QCGISEKEAR RMDRFIQLGM AAAIEAFKDS GLEVTEENAE RIGVHLGSGI GGISSIEDTT
RTIAERGPRR VSPFYIPMAI INMISGDLSV MYGFKGIGDA ARIIEYGDAD VMIAGGAEAA
VTPTALAGFG NAKALSTRND SPETASRPWD KDRDGFILGE GAGVVVLEEI EHAKRRGARI
YCELVGFGMS GDAYHMTSPP ENGEGAARCM RNALRNAHLG PEAVQYINAH GTSTPLGDKA
ETMAVKTAFG DHAPKLAVSS TKSMTGHLLG AAGGVEAVYS ALAIHHQVAP PTINLVTPDP
DCDLDYVPNT ARDMKIDVAL SNSFGFGGTN GTLIFRRFG
//
