ID A0A0S8GUK4_9BACT Unreviewed; 599 AA.
AC A0A0S8GUK4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 13-SEP-2023, entry version 28.
DE RecName: Full=Excinuclease ABC subunit C {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=AMS25_17890 {ECO:0000313|EMBL:KPK75947.1};
OS Gemmatimonas sp. SM23_52.
OC Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC Gemmatimonadaceae; Gemmatimonas.
OX NCBI_TaxID=1703359 {ECO:0000313|EMBL:KPK75947.1, ECO:0000313|Proteomes:UP000051975};
RN [1] {ECO:0000313|EMBL:KPK75947.1, ECO:0000313|Proteomes:UP000051975}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM23_52 {ECO:0000313|EMBL:KPK75947.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPK75947.1}.
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DR EMBL; LJUM01000214; KPK75947.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8GUK4; -.
DR PATRIC; fig|1703359.3.peg.3167; -.
DR Proteomes; UP000051975; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0009381; F:excinuclease ABC activity; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd10434; GIY-YIG_UvrC_Cho; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR Gene3D; 3.30.420.340; UvrC, RNAse H endonuclease domain; 1.
DR HAMAP; MF_00203; UvrC; 1.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR047296; GIY-YIG_UvrC_Cho.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004791; UvrC.
DR InterPro; IPR001162; UvrC_RNase_H_dom.
DR InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR NCBIfam; TIGR00194; uvrC; 1.
DR PANTHER; PTHR30562:SF1; UVRABC SYSTEM PROTEIN C; 1.
DR PANTHER; PTHR30562; UVRC/OXIDOREDUCTASE; 1.
DR Pfam; PF01541; GIY-YIG; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF08459; UvrC_RNaseH_dom; 1.
DR SMART; SM00465; GIYc; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS50164; GIY_YIG; 1.
DR PROSITE; PS50151; UVR; 1.
DR PROSITE; PS50165; UVRC; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881}.
FT DOMAIN 3..82
FT /note="GIY-YIG"
FT /evidence="ECO:0000259|PROSITE:PS50164"
FT DOMAIN 193..228
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT DOMAIN 245..472
FT /note="UvrC family homology region profile"
FT /evidence="ECO:0000259|PROSITE:PS50165"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KPK75947.1"
SQ SEQUENCE 599 AA; 67755 MW; 4B8A13CCF5EF1869 CRC64;
LPASAGVYVL RDRRGKPLYV GKAKSLRDRV RSYFRDERSS QHKPPEMVRK IADFDTIVTD
SEAEALILES NLIKEYAPRF NIRLRDDKTY PYIKVTVGER FPRVFVTRRL VKDGSRYFGP
YADVGHMRRA LRAIKELYTI RSCHYDLPRQ APSRPCLDYY IGRCKAPCVR CQSESEYREM
IEEVLLVLQG HTGRLAEKLS ARMAEAAQAL EFERAAELRD VLRGLQEIER RQLAIDPRGG
DLDALSVVRD GDTACGVILK IREGKLLGRE AHFLGNVEGE EEGSLLSAFV ARYYLSQQEL
GKELLIPFAF SDQAAVAEHL RQRTGRAFTV RVPRRGIKRN LVARAEENAR HLLEERRLLE
GEAERRAPPA LYALRGELNL ERVPRSIVGF DVSNIHGSDA VGAAVWFENA HPLKGEYRRF
KIQSVEGVDD YAAMQEIVGR YFARRIKEDK RLPDLVLVDG GRGQLSAAAQ ALERAGALDT
PLVALAKREE LVFTLDRQEA LRLARREPAL QLLQHIRDEA HRFGIQYHRK RRGARTVRSA
LQDIPGVGPA REKALLSSLG SLKALRAATV EEIAQVPGIS EHLASEIFRS LREENGSSE
//
