ID A0A0S8K4V0_9BACE Unreviewed; 606 AA.
AC A0A0S8K4V0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Penicillin-binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMS26_03040 {ECO:0000313|EMBL:KPL16881.1};
OS Bacteroides sp. SM23_62.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1703352 {ECO:0000313|EMBL:KPL16881.1, ECO:0000313|Proteomes:UP000050819};
RN [1] {ECO:0000313|EMBL:KPL16881.1, ECO:0000313|Proteomes:UP000050819}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM23_62 {ECO:0000313|EMBL:KPL16881.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPL16881.1}.
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DR EMBL; LJUP01000015; KPL16881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8K4V0; -.
DR PATRIC; fig|1703352.3.peg.937; -.
DR Proteomes; UP000050819; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..214
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 252..576
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 606 AA; 68223 MW; 75B8FDA1761BA768 CRC64;
MNPYAGRKYV IGGIIILTGI IFLIRLFFIQ VVESSYKSTA ERNARHIEIQ YPARGLIYDR
NGEILVYNEA AYDLMVTPGQ LQAFDTVDFC RILEIPKNEV IRRIRTASDY SVFKPSIFLR
QISSVTYAVM QEKLYKFPGF FVQPRTLRKY PRDIAAHALG FVGEVSEEDI EENEYYQMGD
YIGVTGIELA YEEVLRGVKG RKIFLVDVHN RVKGSYQGGR ADRKAEVGEN VVSTLDAGLQ
EYGEKLMTKF RGSIVALEPS TGEVLALVTS PAYKPSLLVG RIRSENFLYL SQDTLKPWFN
RALMAFYAPG STFKTVNGAI ALQEGVITTA SEYYCDLGFH MGGYSVACHM HPSPLDFRGA
VQHSCNAYFN YVYRAILTDP EFESTAEAYM NWRDHVMSFG FGDYLHSDFE NELPGFVPDD
QYYNNIYGEG HWNFFTVRSL SIGQGELGIT PLQMANLAGI IANRGFYYTP HIIKEVEGQD
RIDERFLEKH NTRIDSIHFA AVADGMEGAV NRSGGTAWRA RIADIIVCGK TGTAENPHGE
DHSVFIAFAP KDNPQIAISV CVENGGFGNI WAAPIAGLMA EKYLRDTITR PYMEEYVLRG
VRLDQQ
//
