ID A0A0S8KMD0_9CHLR Unreviewed; 845 AA.
AC A0A0S8KMD0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=AMJ93_06135 {ECO:0000313|EMBL:KPL22874.1};
OS Anaerolineae bacterium SM23_84.
OC Bacteria; Chloroflexota; Anaerolineae.
OX NCBI_TaxID=1703388 {ECO:0000313|EMBL:KPL22874.1, ECO:0000313|Proteomes:UP000052016};
RN [1] {ECO:0000313|EMBL:KPL22874.1, ECO:0000313|Proteomes:UP000052016}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM23_84 {ECO:0000313|EMBL:KPL22874.1};
RX PubMed=25922666; DOI=10.1186/s40168-015-0077-6;
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RT "Genomic resolution of linkages in carbon, nitrogen, and sulfur cycling
RT among widespread estuary sediment bacteria.";
RL Microbiome 3:14-14(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPL22874.1}.
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DR EMBL; LJUZ01000068; KPL22874.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S8KMD0; -.
DR Proteomes; UP000052016; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 660..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 684..704
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 716..735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 755..777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 789..808
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 218..344
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 686..814
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 845 AA; 90665 MW; 0318DF2E52FB75F1 CRC64;
MFQRLGRFAA KYRIPIIVGW VALAIILTLV APGLEEVSTA KQEDFLPANA PFVRAAEIQE
RVFPEQSAAS ASMVIVDAGP GGEVHDPDVL AFLSGLESWL NSDDAPANII VAAGPVTMPE
LADKLISPNN RIALVGVQLS TITDARATVE AVDAIDQWLQ RNTPDGIDVY QSGEAALNAQ
SEEASFQTMD RTLLITLALV IVALLAIYRS PVSPLIPLFA VTLALIVTIG VLGLLADAGV
VSVISQMNAI LVVVMYGAGT DYNLFLISRF REEMADTEKE EATKRTVRLV GETISSSAGT
VFVGFMSLCF AEMGLFKSAG PMLAIGIVVS LLTGLTLVPA LLATLGNWAF WPSKARHRSS
GRLYGFTSKL ASSRPLLTIL VIVAVMAPLS VYGLTRDLNY DMLSELPADI PSVQGYYLLQ
EHMGAGVLFP LNVTLTDRRP ELMAEEIARL TDELYALEGV VDVRGLNPPL GYEDEQFKRL
LGVDHQLELL LGMWATPPEG QPVDPEQAAA AMEGMKRYLN ALAERFPEIA QDTNLLTAQG
ILDSGLMGMA ARQEELLAAL SGLVGRFQAI DAAYLLPPTG EGELFAALGP VFHEYVAADG
VSYRLEVVLA DPVGESGMDV VGRVRNILKG YKGDGDAVVS GATVIYADIR DIMSRDKIRA
FGFIMGGIFL VLLLMLRSAV APTYLIATVL LSFTCTLGIT NLFFDKVMGV ERLSWILPLF
MFVFLVALGI DYSIFLFGRI KEEVGHYGIQ EGVHVAVAAT GAIISSAGII LAGTFAGMMA
GEVQFLKQLG FAVSVGVLID TFVVRTILDP ALAALFGRWT WWPGGVPKAT ESRGVTPTSE
SPSRA
//
