ID A0A0S9C7L0_9MICC Unreviewed; 769 AA.
AC A0A0S9C7L0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Glycosyl hydrolase {ECO:0000313|EMBL:KQN89629.1};
GN ORFNames=ASE96_05620 {ECO:0000313|EMBL:KQN89629.1};
OS Arthrobacter sp. Leaf69.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1736232 {ECO:0000313|EMBL:KQN89629.1, ECO:0000313|Proteomes:UP000051467};
RN [1] {ECO:0000313|EMBL:KQN89629.1, ECO:0000313|Proteomes:UP000051467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf69 {ECO:0000313|EMBL:KQN89629.1,
RC ECO:0000313|Proteomes:UP000051467};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQN89629.1, ECO:0000313|Proteomes:UP000051467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf69 {ECO:0000313|EMBL:KQN89629.1,
RC ECO:0000313|Proteomes:UP000051467};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+);
CC Xref=Rhea:RHEA:19433, ChEBI:CHEBI:15378, ChEBI:CHEBI:18391,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58759, ChEBI:CHEBI:456216;
CC EC=2.7.1.12; Evidence={ECO:0000256|ARBA:ARBA00001329};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- PATHWAY: Carbohydrate acid metabolism. {ECO:0000256|ARBA:ARBA00004761}.
CC -!- SIMILARITY: Belongs to the gluconokinase GntK/GntV family.
CC {ECO:0000256|ARBA:ARBA00008420}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQN89629.1}.
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DR EMBL; LMLR01000010; KQN89629.1; -; Genomic_DNA.
DR RefSeq; WP_056429221.1; NZ_LMLR01000010.1.
DR AlphaFoldDB; A0A0S9C7L0; -.
DR STRING; 1736232.ASE96_05620; -.
DR OrthoDB; 9795716at2; -.
DR Proteomes; UP000051467; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046316; F:gluconokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd02021; GntK; 1.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR006001; Therm_gnt_kin.
DR NCBIfam; TIGR01313; therm_gnt_kin; 1.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01202; SKI; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KQN89629.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 219..538
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
SQ SEQUENCE 769 AA; 82467 MW; A6B571873DDC1738 CRC64;
MTGPRIVVMG VSGCGKTTIG DLVARGLGAP FLDGDSLHPV ENVAKMAAGI PLTDEDRWPW
LATVGSELAN AGDGGLVLAC SALKRCYRDA IRALAPGTVF LHLHGSKEVL GSRLEGRSGH
FMPAALLDSQ LATLEPLESD ETGIVVDIAA PVSQVVTEAL AGIAAVAGSA AGTGTRAGDP
SGTAGTRPRE FDVDLRAAPF NLDDDAVAWV DATIAGMSLE EKIGQLFINH NNDYSPEYLD
GVLENYHVGG MRYRPGPSAA VQEHIRYAQS KARIPLLVAS NPEMGGAGSC DDGTFVSTHL
QAGSHPDKSI ARRMGQVAGV ETAALGCNWA FAPIVDIHYN WRNTVISTRA FGNTSEIVVE
RAKEYFDGIS ESPTACAMKH FPGDGMDERD QHGVTSYNTL GYEEWNRTYG HVYREMIGHG
VQSIMIGHIG APQLSRHFRP GLADKDIMPA TLAPELLQDL LRGELGFNGL ILTDASQMIG
LTQAMKRKDL VPATIAAGCD MFLFFRNPAE DFQYMLDGYK SGVISDQRLH DALRRILALK
ASLGLHRKSA AELVPPADAL GVIGSDAHRA VAAEIADKTV ALVKDTANNL PITPETHKRI
RLYGISGGAD FTRADPLAYL DTVKAELESA GFEVHLFKTA DQREAAGETG VNFMSVISEE
ATGDYADKYD AAFVFANVKG FAQEAAIRIK WSTPMAAEIP WYVTEVPTVF VSLNQPNHLI
DVPMVKTAIH AHAGTPEAIR ATIGKIQGKS EFQGTFNENV FCDSFDTRL
//
