ID A0A0T1W699_9MYCO Unreviewed; 303 AA.
AC A0A0T1W699;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:KQY04216.1};
GN ORFNames=ASD37_19855 {ECO:0000313|EMBL:KQY04216.1};
OS Mycobacterium sp. Root135.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1736457 {ECO:0000313|EMBL:KQY04216.1, ECO:0000313|Proteomes:UP000051127};
RN [1] {ECO:0000313|EMBL:KQY04216.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY04216.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQY04216.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY04216.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQY04216.1}.
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DR EMBL; LMEZ01000007; KQY04216.1; -; Genomic_DNA.
DR RefSeq; WP_056555623.1; NZ_LMEZ01000007.1.
DR AlphaFoldDB; A0A0T1W699; -.
DR STRING; 1736457.ASD37_19855; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000051127; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:KQY04216.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000051127}.
FT DOMAIN 7..276
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 303 AA; 31019 MW; AE3FF8490078ADB6 CRC64;
MSLPEHVTIR EVCLRDGLQI EAPISLAAKL ALLEAVVATG VREVEATAFV SPSKVPALAD
AEALAAELPR FRDTHGVEFS ALVAGPGGAN RAIAAGMDSI EYVVSASDAH SRANVGRSTA
ESTDLIADIA RIAHEGGATI EVIVATAWDC PFDGPTDPAR VVDIVTAAVE IGADRIAIAD
TIGTTTPRRV TTLVDVLRPV VDDLPFGAHF HNTRGAGLAS AYAAVTAGIR RLDSSAGGLG
GCPFAPGATG NIATEDLVYL LRDSGIGTDV DLRAAIRAAG VARDVVGHDL PSALLRAGDR
VLG
//
