ID A0A0T1WFP7_9MYCO Unreviewed; 960 AA.
AC A0A0T1WFP7;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ASD37_08550 {ECO:0000313|EMBL:KQY08005.1};
OS Mycobacterium sp. Root135.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1736457 {ECO:0000313|EMBL:KQY08005.1, ECO:0000313|Proteomes:UP000051127};
RN [1] {ECO:0000313|EMBL:KQY08005.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY08005.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQY08005.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY08005.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQY08005.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMEZ01000004; KQY08005.1; -; Genomic_DNA.
DR RefSeq; WP_056550630.1; NZ_LMEZ01000004.1.
DR AlphaFoldDB; A0A0T1WFP7; -.
DR STRING; 1736457.ASD37_08550; -.
DR OrthoDB; 4747874at2; -.
DR Proteomes; UP000051127; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR004707; MmpL_fam.
DR InterPro; IPR000731; SSD.
DR NCBIfam; TIGR00833; actII; 1.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051127};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 766..784
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 790..813
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 820..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 860..888
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 900..928
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 224..351
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 960 AA; 103902 MW; 376B32686442ECDB CRC64;
MSTHHAEGTT RTDRIGHTIR RFSPLIVLFW LALAVATNVF VPQLEKVAEA HNVSLSPQDA
PSLQASKEIG KKFQQYDSDS AAMIVLEGDQ PLGADAHHYY DDLVRKLSQD TTHVEHVQDF
WGDPLTAAGS QSSDGKAALL QVNLAGNQGE SLSNQSVDSI RDIVNRSTPP PGVHAYVTGA
APLVTDQFEV GRQGTLKTTL ITLGVIALML FFIYRRLTTV FLVIFTVMIE LTASRGVVAV
LANAGIIELS TYSTNLLTLL VIAAGTDYAI FILGRYHEAR HVGEDRVTAY ATMYRGTSHI
ILGSGLTIAG AVFCLTFTRL PYFQSLGVPA ATGVLVAVVA ALTLAPALLS IGRHFGLFEP
ARPLNTRGWR RIGTAIVRWP GPILVATIAV ALIGLLALPA YKTSYDARPY IPATAPANVG
YAAAERHFSQ ARLNPELLMV EADHDLRNPT DMILLERVAK AVFHTDGIAQ VQSITRPLGT
PLDHTSIPFQ ISAGSSAQIQ NLPFQQARAD DLLKQVATID DGVRVLRQQY ALQQQSAEVT
DEQAKAFQQT VATAQDLRDK IANFDDFFRP LRSYFYWEPH CFDIPVCAAL RSIFDALDGI
DALTDQLGDV AGSIAKLDAL QPKLLALFPP QLANQQTNRD LTMTNYATNS GINNQSAASL
QNATALGQAY DASKTDDSFY LPPEAFTNPE FIRGLKLFLS PDGKAAQMII THEGDPATPE
GISHIDGIRH AAQEAVKGTP LAGSKLYLAG TAATYKDIQD GAKYDLMIAA IAAMSLILLI
MMFITRSLVA AFVIVGTVAL SLGASFGLSV LIWQDLLGID LYWIVLALAI ILLLAVGSDY
NLLLISRFKE EIHAGLNTGI IRAMAGSGSV VTAAGLVFAA TMASFVFADL RILGQIGTTI
ALGLLFDTLI VRSFMTPSIA ALLGRWFWWP LVVRPRPARN WPKADESRQA GRQLPLWEDA
//
