ID A0A0T1WLI2_9MYCO Unreviewed; 1006 AA.
AC A0A0T1WLI2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ASD37_02240 {ECO:0000313|EMBL:KQY10208.1};
OS Mycobacterium sp. Root135.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1736457 {ECO:0000313|EMBL:KQY10208.1, ECO:0000313|Proteomes:UP000051127};
RN [1] {ECO:0000313|EMBL:KQY10208.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY10208.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQY10208.1, ECO:0000313|Proteomes:UP000051127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root135 {ECO:0000313|EMBL:KQY10208.1,
RC ECO:0000313|Proteomes:UP000051127};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQY10208.1}.
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DR EMBL; LMEZ01000001; KQY10208.1; -; Genomic_DNA.
DR RefSeq; WP_056549682.1; NZ_LMEZ01000001.1.
DR AlphaFoldDB; A0A0T1WLI2; -.
DR STRING; 1736457.ASD37_02240; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000051127; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR InterPro; IPR023908; xxxLxxG_rpt.
DR NCBIfam; TIGR03057; xxxLxxG_by_4; 1.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051127};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 831..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 857..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 886..908
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 929..957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 227..357
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 1006 AA; 105553 MW; C65736693EF034B5 CRC64;
MRERTISAAK TSGEYSERLG ALARFTVRHK ALVIGAWVGL AVVLALLFPQ LETVVQKQSV
QLIPRDVASF QTLDRMSEAF GEQGSKTMLF VAMEDPAGLT PSARTQYTDL VSRLRADTTH
VLLVQDLLAD PVTATQALSQ DGKAWYLPVG VAGTLGDPAA AESVTAVRAI AADAFAGSST
TVRVTGPPST FSDQIAEAEH DLLFISIATA GLIALILLIV YRSVFTALLP LLVIGISLAV
GRGVLSVLGE LGMPVSQFTV AFMTAILLGA GTDYTVFLIS RYHEQRRAQV APDQAVEHAT
ASIGRVILAS AATVALAFAA MVFANLSVFA GMGPACAVAV LVGFVATVTL LPPVLSLAAK
RGIGEPKSDR TRRYWNSVAV AVVRKPVPLL LVSLAILLAL SAVATTMTLS YDDRKGQPAT
TASNEGYQLL DRHFRTDVVI SEFLVVESPT DMRTGKGLAD LDEMASRIAQ VPGVTKVSGV
TRPAGARLEQ AQLGWQNGQI GDKMAGAVDD GNARKDDLAK LTGGADQLAG GLAQLDTTLR
TALTPLTGIL DQAQSAGRKV DQFRPLLSQL SATAPAVDQA LRSGPGLRPL AEQADGAIAT
IDPLVGALNT SPWCATTPQC AQIRDQVQVL TTLRNAGFFT QVAGLGDTVG QNASVADTLA
GVQTAVTSLD KAFGALGDPA NLAGNVRRLQ DGIGQLASGA QALATGVHTL ADSNIDMLSG
MSQIATQLQN SARASTGSDT SSGFFLPPNA FENRQFADVA KQFLSRDGKT ARFLVESSND
PYSAEAMDLS HQMVAVAEAA RPNTSLAQAR ISVAGFPAVN SDIQRLLTAD FIQLAASTLL
IVGLILVLLL RALLAPLYLL GTVVLNYTAS LGIGVLVFQW GLGGEIAWPV PLLAFIILVA
VGADYNMLLV SRLKEESTRN IRVGVLRTVA STGSVITSAG IIFAVSMLGL MVGSIAIMIQ
AGFIIGCGLL LDTFVVRTLT VPAIAVLLRE ASWWPHRPTT PQRRTS
//
