ID A0A0T5NQD6_9RHOB Unreviewed; 404 AA.
AC A0A0T5NQD6;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=4-hydroxytetrahydrobiopterin dehydratase {ECO:0000313|EMBL:KRS10894.1};
GN ORFNames=XM53_18910 {ECO:0000313|EMBL:KRS10894.1};
OS Roseovarius atlanticus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=1641875 {ECO:0000313|EMBL:KRS10894.1, ECO:0000313|Proteomes:UP000051295};
RN [1] {ECO:0000313|EMBL:KRS10894.1, ECO:0000313|Proteomes:UP000051295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R12B {ECO:0000313|EMBL:KRS10894.1,
RC ECO:0000313|Proteomes:UP000051295};
RA Li G., Lai Q., Shao Z., Yan P.;
RT "The draft genome sequence of Roseovarius sp.R12b.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRS10894.1}.
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DR EMBL; LAXJ01000026; KRS10894.1; -; Genomic_DNA.
DR RefSeq; WP_057796196.1; NZ_LAXJ01000026.1.
DR AlphaFoldDB; A0A0T5NQD6; -.
DR STRING; 1641875.XM53_18910; -.
DR PATRIC; fig|1641875.4.peg.2313; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000051295; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 263..378
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 404 AA; 44701 MW; C2605CD9E560AD84 CRC64;
MEKANDSRLP VTVLSGFLGA GKTTLLNRVL NNREGRRVAV IVNDMSEVNI DADLVREGGA
NLSHTDETLV EMSNGCICCT LRDDLLDEVR RLAGEGRFDY LLIESTGISE PLPVAATFDF
RDEAGDSLSD VSRLDTMVTV VDAVNLLEDY SSHDFLSDRG ETLGEADERT LVHLLTDQIE
FADVVVLNKI SDAGPERTDA ARKIIRSLNA DARIIETDHS DVAADAILDT GLFDFEKAHE
HPMWAKELYG FADHVPETEE YGVASFVYRA RQPFEPEKIM AVLNGNLPGV IRAKGHFWIA
TRPDWVAEYS LAGALSSVTP LGQWWATVPK ERHPEHAGAQ EYLRAHWQEP WGDRRQEIVF
IGAGIDWPAL KARLDAALVP ESAALGPDSL PHLPDPFPAW RRAS
//
