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Database: UniProt
Entry: A0A0T6UUH3_9PSED
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ID   A0A0T6UUH3_9PSED        Unreviewed;       494 AA.
AC   A0A0T6UUH3;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   25-OCT-2017, entry version 15.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AO726_06620 {ECO:0000313|EMBL:KRW61687.1};
OS   Pseudomonas sp. TTU2014-080ASC.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1729724 {ECO:0000313|EMBL:KRW61687.1, ECO:0000313|Proteomes:UP000051864};
RN   [1] {ECO:0000313|EMBL:KRW61687.1, ECO:0000313|Proteomes:UP000051864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TTU2014-080ASC {ECO:0000313|EMBL:KRW61687.1,
RC   ECO:0000313|Proteomes:UP000051864};
RA   Webb H.E., Bugarel M., Den Bakker H.C., Nightingale K., Granier S.A.,
RA   Loneragan G.H.;
RT   "Carbapenem-non-susceptible Bacteria Recovered from the Faeces of
RT   Dairy Cattle.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRW61687.1}.
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DR   EMBL; LKKK01000002; KRW61687.1; -; Genomic_DNA.
DR   RefSeq; WP_058067963.1; NZ_LKKK01000002.1.
DR   EnsemblBacteria; KRW61687; KRW61687; AO726_06620.
DR   Proteomes; UP000051864; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000051864};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051864}.
FT   DOMAIN      191    396       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      402    471       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     199    206       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   494 AA;  55522 MW;  D79CBDE20C3C7267 CRC64;
     MSVELWQQCV ELLRDELPAQ QFNTWIRPLQ VDAEGGELRV YAPNRFVLDW VNEKYLGRLL
     ELLTERSGGM VPSLSLLIGS KRSSVPRPAL TPNVVTPTPA PAPVITAPAV EEPAPVDMSP
     SEPSRASFDS MAGSAAASQP VRAERTVQVE GGLKHTSYLN RTFTFDNFVE GKSNQLARAA
     AWQVADNPKH GYNPLFLYGG VGLGKTHLMH AVGNHLLQRN PNAKVVYLHS ERFVADMVKA
     LQLNAINEFK RFYRSVDALL IDDIQFFAKK ERSQEEFFHT FNALLEGGQQ VILTSDRYPK
     EIEGLEERLK SRFGWGLTVA VEPPELETRV AILMKKADQA KVELPHDAAF FIAQRIRSNV
     RELEGALKRV IAHSHFMGRD ITIELIRESL KDLLALQDKL VSIDNIQRTV AEYYKIKISD
     LLSKRRSRSV ARPRQVAMAL SKELTNHSLP EIGDAFGGRD HTTVLHACRK IAELKESDAD
     IREDYKNLLR TLTT
//
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