ID A0A0T6UXY4_9PSED Unreviewed; 122 AA.
AC A0A0T6UXY4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Cyclic diguanosine monophosphate-binding protein {ECO:0000256|PIRNR:PIRNR028141};
DE Short=c-di-GMP-binding protein {ECO:0000256|PIRNR:PIRNR028141};
DE AltName: Full=Pilz domain-containing protein {ECO:0000256|PIRNR:PIRNR028141};
GN ORFNames=AO726_05470 {ECO:0000313|EMBL:KRW62864.1};
OS Pseudomonas sp. TTU2014-080ASC.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1729724 {ECO:0000313|EMBL:KRW62864.1, ECO:0000313|Proteomes:UP000051864};
RN [1] {ECO:0000313|EMBL:KRW62864.1, ECO:0000313|Proteomes:UP000051864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTU2014-080ASC {ECO:0000313|EMBL:KRW62864.1,
RC ECO:0000313|Proteomes:UP000051864};
RA Webb H.E., Bugarel M., Den Bakker H.C., Nightingale K., Granier S.A.,
RA Loneragan G.H.;
RT "Carbapenem-non-susceptible Bacteria Recovered from the Faeces of Dairy
RT Cattle.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Binds the second messenger bis-(3'-5') cyclic dimeric
CC guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per
CC monomer. May play a role in bacterial second-messenger regulated
CC processes. Binding to c-di-GMP induces a conformational change of the
CC C- and N-termini resulting in the exposure of a highly negative surface
CC on one side of the protein to a possible effector protein.
CC {ECO:0000256|PIRNR:PIRNR028141}.
CC -!- SUBUNIT: Monomer in both c-di-GMP-bound and free forms.
CC {ECO:0000256|PIRNR:PIRNR028141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRW62864.1}.
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DR EMBL; LKKK01000001; KRW62864.1; -; Genomic_DNA.
DR RefSeq; WP_058067018.1; NZ_LKKK01000001.1.
DR AlphaFoldDB; A0A0T6UXY4; -.
DR STRING; 1729724.AO726_05470; -.
DR OrthoDB; 5298508at2; -.
DR Proteomes; UP000051864; Unassembled WGS sequence.
DR GO; GO:0035438; F:cyclic-di-GMP binding; IEA:InterPro.
DR Gene3D; 2.40.10.220; predicted glycosyltransferase like domains; 1.
DR InterPro; IPR027021; C-di-GMP_BP_PA4608.
DR InterPro; IPR009875; PilZ_domain.
DR Pfam; PF07238; PilZ; 1.
DR PIRSF; PIRSF028141; C-di-GMP_BP_PA4608; 1.
DR SUPFAM; SSF141371; PilZ domain-like; 1.
PE 4: Predicted;
KW c-di-GMP {ECO:0000256|PIRNR:PIRNR028141};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR028141};
KW Reference proteome {ECO:0000313|Proteomes:UP000051864}.
FT DOMAIN 7..103
FT /note="PilZ"
FT /evidence="ECO:0000259|Pfam:PF07238"
SQ SEQUENCE 122 AA; 13903 MW; 28C9093425E1F31A CRC64;
MSASGNERRR FQRIEFDAPT TLKQGERSWN AELLDISLKG LLIKRPEHWN ADPNENFTVQ
IDLTEDTHVV LDAVLTRFHG EVLGFVCRHI DLDSISHLRR LVELNLGDDS LLERELAALG
DA
//
