ID A0A0T7BNM2_9CYAN Unreviewed; 1835 AA.
AC A0A0T7BNM2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=IJ00_04740 {ECO:0000313|EMBL:AKG20705.1};
OS Calothrix sp. 336/3.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Calotrichaceae;
OC Calothrix.
OX NCBI_TaxID=1337936 {ECO:0000313|EMBL:AKG20705.1, ECO:0000313|Proteomes:UP000065745};
RN [1] {ECO:0000313|EMBL:AKG20705.1, ECO:0000313|Proteomes:UP000065745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=336/3 {ECO:0000313|EMBL:AKG20705.1,
RC ECO:0000313|Proteomes:UP000065745};
RX PubMed=25614574;
RA Isojarvi J., Shunmugam S., Sivonen K., Allahverdiyeva Y., Aro E.M.,
RA Battchikova N.;
RT "Draft genome sequence of calothrix strain 336/3, a novel h2-producing
RT cyanobacterium isolated from a finnish lake.";
RL Genome Announc. 3:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP011382; AKG20705.1; -; Genomic_DNA.
DR STRING; 1337936.IJ00_04740; -.
DR KEGG; calh:IJ00_04740; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000065745; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000065745}.
FT DOMAIN 10..279
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1558..1815
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1835 AA; 205893 MW; 69C7360102C809ED CRC64;
MQRGLMFPGY IINEIIYEGI ETTVYRASSE KNQTSVIIKA LKAEYPSVEM VTRIKHEFRM
MENLNLPGVI QVEDLQVCQN RWFLVMEDIG GVSLGNFLQD MGDSDSKKLG VGEFLQIAVQ
LAQGLISLHQ EEIIHKDIKP ANIIINPQTG EVKITDLSIA SRFTHGATQL LHPEQMEGTL
AYMSPEQTGR MNRSIDYRSD FYSLGVTFYE MLAGCLPFTS QDALELVHCH IAKQAPPLQE
IIPEIPLAIA AIVDKLMAKN AEERYQTADG LLKDLEDCFQ QWQRGGRITN FQLGKGDRPS
QLLIPQKLYG REKQVQQILA AFERVNQNNS QKKILPEMIL VSGYSGIGKS SLVNEVHKPI
VRQKGYFVSG KFDQLQRNIP YASIIQALQS LIQQILTEDS QKLTYWRQRL HQALGDNGQI
MVNVIPELEY IIGKQPMVAE LGITETQNRF IRIFQSLIRV FAAPSHPLVI FLDDLQWADS
ASLNFLQILI TNPENQYLLL IGAYRDNEVS AVHPLMKTIS LIREAGISIT NIILSPLNLH
HIQELVRETL VLTADNLSTE ELAELLFNKT QGNPFFLNQL LKILYQEKLL TFDINQGGWQ
WDLQQIQAAG IGDKSIVELM AANIHKLPSL TQSILQKAAC IGAKFTLDVI AAVSEKRVAE
VAVALDSALH MGLILPLNND YRIPLLFAEE ELANFRLDDS RPAYRFLHDR VQQAAYSLIP
ESEKQHTHYH IGQLLLQNTL PEAIENNIFD IVNQFNMAIA NIDASQKLQL AELNLIAGSR
AKSAAAYDAA YSYLRTGFQL LSKNIWQEDY KFALRYHEAV AQLAYLCGDF AVTEDCTQAI
AHQATSLLDI VAAQEIQILA NLAQNRLLDA VDLALKILKQ LGIKLPSRPN MLEVLQGLVI
TRLNLLDKKA ASLIDLPEMR QQEQLAAMRI LSTVTSAAYL SVPNLLPLLV FSQIRLSVKY
GNTALSAVGY AQYGFILSGV VSDIATGFAF GQLALAIVDK FRARELQAKV LVLVYGFNYH
WQKPLGETLK FLESAYQLGL ETGEIEYTTW AALFYCMYAY YLGRDLQELH TEISAYRQSI
QQLKQEKALT YIQVFEYTVN ALLDKPVIPL DFALINDDTG KFFAHLQELQ LKYLFGDYQG
AIAQGKVAVT YLQSVVGTYN VGVYHFYQAL ALLAVYPQLG KSEQQQALAT VNSYQRKLEK
WAKYSPTSYQ HKVALLVAEK YGIFGQKDKA MAYYERAIAL AQANNFLSEV ALAYERTALF
YLSIQQPKIA KVYMTDAYYN YLQWGATAKV KQLQKNHPDL IIQTLTLGNT IDINSNISSR
TYIPQEGTIS ENIHILDLAT LLKASETIQS SLHIENLPSC LLQIIIENTG AQTGFLVLQQ
QEQLIIVAMH DGVEIITSRS TMESANIPHT LINYAARTYQ PLVINDAQSH PLCASDSYIL
TVKAKSVLCF PIFYQGKFIG LFYLENRLTT GAFTPQHWEI LKILASQAAI ALHNSQLYTQ
EQQKSLQLQT SLEELQLTQT LLQQKAHDLE TAILQLQQTQ SQLVHTEKIS SLGQLVAGVA
HEVNNPVGFI SGNLDYTQEY VQQLIHHLQL YQQHFTEIPE AILQDAKKID LDYLITDLPK
MIDSMQLGAS RITDIMQSLR NFSRNDGNDK KAVDIHEGIN TTIMILSHRL KAKATRPQIV
IVKEYGDLPL IECYPGQLNQ VFMNLIANAI DALEESNQGK TYTEIEKNPN TITINTSILN
DGVCIRIADN GMGMSQEVQD KLFNAFFTTK PEGKGTGLGL SISYQIVTEK HGGSLKCNSA
PGKGAEFIIT LPGAKEIPED KVRSNTNSQF AIRNS
//
