ID A0A0U0WXY4_9MYCO Unreviewed; 511 AA.
AC A0A0U0WXY4;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ESX-4 secretion system protein eccD4 {ECO:0000313|EMBL:CPV42767.1};
DE SubName: Full=Type VII secretion integral membrane protein EccD {ECO:0000313|EMBL:RIT43948.1};
GN Name=eccD4_1 {ECO:0000313|EMBL:CPV42767.1};
GN Synonyms=eccD {ECO:0000313|EMBL:RIT43948.1}, eccD4
GN {ECO:0000313|EMBL:CPW99980.1};
GN ORFNames=D2E76_02605 {ECO:0000313|EMBL:RIT43948.1}, ERS075579_01424
GN {ECO:0000313|EMBL:CPV42767.1}, ERS075604_01953
GN {ECO:0000313|EMBL:CPW99980.1};
OS Mycobacteroides abscessus.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacteroides.
OX NCBI_TaxID=36809 {ECO:0000313|EMBL:CPV42767.1, ECO:0000313|Proteomes:UP000045782};
RN [1] {ECO:0000313|EMBL:CPW99980.1, ECO:0000313|Proteomes:UP000042347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAP113 {ECO:0000313|EMBL:CPW99980.1,
RC ECO:0000313|Proteomes:UP000042347};
RG Pathogen Informatics;
RA Murphy D.;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CPV42767.1, ECO:0000313|Proteomes:UP000045782}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAP088 {ECO:0000313|EMBL:CPV42767.1,
RC ECO:0000313|Proteomes:UP000045782};
RA Murphy D.;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:RIT43948.1, ECO:0000313|Proteomes:UP000284557}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G143 {ECO:0000313|EMBL:RIT43948.1,
RC ECO:0000313|Proteomes:UP000284557};
RA Ye M., Xu L., Zou Y., Li B., Guo Q., Zhang Y., Zhan M., Xu B., Yu F.,
RA Zhang Z., Chu H.;
RT "Linezolid Resistance in Mycobacterium abscessus: MIC Distribution and
RT Comprehensive Investigation of Resistance Mechanisms.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EccD/Snm4 family.
CC {ECO:0000256|ARBA:ARBA00006162}.
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DR EMBL; CSWP01000002; CPV42767.1; -; Genomic_DNA.
DR EMBL; CSXT01000004; CPW99980.1; -; Genomic_DNA.
DR EMBL; QXBN01000001; RIT43948.1; -; Genomic_DNA.
DR RefSeq; WP_005055988.1; NZ_UGQJ01000002.1.
DR RefSeq; YP_001704485.1; NC_010397.1.
DR GeneID; 66969184; -.
DR PATRIC; fig|36809.44.peg.3636; -.
DR OMA; VTPFWGR; -.
DR Proteomes; UP000042347; Unassembled WGS sequence.
DR Proteomes; UP000045782; Unassembled WGS sequence.
DR Proteomes; UP000284557; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR044049; EccD_transm.
DR InterPro; IPR006707; T7SS_EccD.
DR InterPro; IPR024962; YukD-like.
DR NCBIfam; TIGR03920; T7SS_EccD; 1.
DR Pfam; PF19053; EccD; 1.
DR Pfam; PF08817; YukD; 1.
DR PIRSF; PIRSF017804; Secretion_EccD1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 136..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..508
FT /note="EccD-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF19053"
SQ SEQUENCE 511 AA; 52234 MW; 80CCFD401A50F7C0 CRC64;
MTHAQSGAEQ RSAVLELCRV SIQAERTQVD LALPTSVPLA LLVGSIVDII NQHVGVPELT
SPEDAVETHW RLSRPGQPPL QMSSTLGELE VRDGDLLILT RSDVAAPDPL FDDVFLAVST
FRTVSAHPWS RNAARILGAS VCGLSALLGA TALLRAGATN PGLLLPIIAV AIALVAMTAA
VFANRVYDDS LASVMLSHCA VGFSAVAGAL FVPGKYGAPH AMLALMVAMV VSILAMRATG
TGTTSLVAVA SASFLGFAAA LGYVLFEPPI YSLGAVLGSV GICAVALSPR VAMVLARLPL
PPVPTQGAPS RPEHSTAPIE AIEGLDGLDT EGDDVEDATA LPPLPDLREK ALRAHAVLTG
LVCGTSAVTA VGAMLAALTF SGAGGHHPTG AHRLSGVVLA GLIALAMMLR ARSHADLAQT
VAINLGGIAI PAAAFAFVAV AYPTAAVFTT VLAAIAAGSA IALGFLVSAR KYSPVARRTV
EIIEYIALSL IVPIAVWVCG VYSAVRGLNL P
//
