ID A0A0U1KV30_9FIRM Unreviewed; 581 AA.
AC A0A0U1KV30;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Periplasmic [Fe] hydrogenase large subunit {ECO:0000313|EMBL:CQR71135.1};
DE EC=1.12.7.2 {ECO:0000313|EMBL:CQR71135.1};
GN ORFNames=SpAn4DRAFT_2113 {ECO:0000313|EMBL:CQR71135.1};
OS Sporomusa ovata.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=2378 {ECO:0000313|EMBL:CQR71135.1, ECO:0000313|Proteomes:UP000049855};
RN [1] {ECO:0000313|Proteomes:UP000049855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Nijsse Bart;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CTRP01000003; CQR71135.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U1KV30; -.
DR Proteomes; UP000049855; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR InterPro; IPR000283; NADH_UbQ_OxRdtase_75kDa_su_CS.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR NCBIfam; NF040763; FeFe_hydrog_A6; 1.
DR PANTHER; PTHR11615:SF345; CATALYTIC SUBUNIT OF IRON-ONLY HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
DR PROSITE; PS00641; COMPLEX1_75K_1; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:CQR71135.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000049855}.
FT DOMAIN 88..127
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 147..177
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 191..219
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 581 AA; 63428 MW; D846D2DB50135233 CRC64;
MGHHASDPNK IVNVTIDGIP VSCPETTLIL DAAKMAGVKI PVLCYHPDLK VRATCRICVV
EVKGQRKLKT ACSNEVWDGA EFITNNPAVR QARKDVLELI LAEHPQDCLK CVRNTSCELQ
QLARDFGISK PLFKNEPKQL PIEDSNGVIV RDMAKCVKCG RCVEMCQEVQ TVGAINTAHR
SVEYEITTAF DRPLQDSTCV YCGQCISVCP VGALYEKDET EKVWQAIDDK EKHVVVQVAP
AVRVALGEEF GLEPGSITTG KMVAALRRLG FDKVFDTDFA ADVTIMEEGS ELLERMTNGG
TLPLITSCSP GWINFVETFY PDLLPHVSTC KSPQQMFGAL AKSYYPEKAG IDAAKIVSVS
IMPCTAKKYE SARPEMNGSG YRDVDVALTT RELARMIKQA GVDFNKLGNE EFDAPLGLST
GAAVIFGTSG GVMEAALRTV YEVVTGKELA NVDFEGVRGL TGVKDAEVDL DGKKVKVAIA
NGLKNARVIL DKIRAGECDY QFVEIMCCPG GCIGGGGQPW GTTKATKEAR MAGLYQADRE
LPIRQSHKNP AVKALYDEYL GKPLGHKSHK LLHTHYHPRQ K
//
