ID A0A0U1KVY6_9FIRM Unreviewed; 695 AA.
AC A0A0U1KVY6;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Cell division protein FtsI [Peptidoglycan synthetase] {ECO:0000313|EMBL:CQR71299.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:CQR71299.1};
GN ORFNames=SpAn4DRAFT_3804 {ECO:0000313|EMBL:CQR71299.1};
OS Sporomusa ovata.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=2378 {ECO:0000313|EMBL:CQR71299.1, ECO:0000313|Proteomes:UP000049855};
RN [1] {ECO:0000313|Proteomes:UP000049855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Nijsse Bart;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CTRP01000004; CQR71299.1; -; Genomic_DNA.
DR RefSeq; WP_021167407.1; NZ_CTRP01000004.1.
DR AlphaFoldDB; A0A0U1KVY6; -.
DR Proteomes; UP000049855; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.30.10.20; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR011927; SpoVD_pbp.
DR NCBIfam; TIGR02214; spoVD_pbp; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:CQR71299.1};
KW Cell division {ECO:0000313|EMBL:CQR71299.1};
KW Glycosyltransferase {ECO:0000313|EMBL:CQR71299.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000049855};
KW Transferase {ECO:0000313|EMBL:CQR71299.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 570..632
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 638..695
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 695 AA; 75812 MW; 4053957840A7461F CRC64;
MAAVSHVTIR KRVAFLFLVI SVIMMGLIGR LLYLQFYKSV WLSENAVDQR IREIPVEAKR
GIIYDRNGRE LAVSVSTESV YAIPAEIRNP EETAAKLAAI LALDETKLTN KLKKRQAFTW
IKRKIEPEIG HQVQMLTLPG IGLTQENRRY YPYDNLAAHV LGFNGIDSQG LDGVEMTFDS
YLKGRSGSIV IEYDARGQEI PNASHRFLPP VEGHNIYLTL DLVIQQIVER ELDRVMKETQ
AKAVTIIAID PRDGGILALA NRPDYNPNKF SEFSPKLWRN IAVSNVYEPG STFKIITTSA
VMSEHLVKAD EKFFDPGEVE VQGRRIHCWK HGGHGSQTFA EVVQNSCNVG FVNVGLRLGR
ESFYRYIDAF GFGQQTNIDL PGEAKGITID RAKATPINIA TMSIGQSIAV TPIQLVTAAA
AVANDGKLLR PQIVREVKDK SGQVIRAFQP DVVRQVLDSS TTKQVKEILE SVVSQGSGRN
AYIEGFKIAG KTGTAQKVGA GGYLPDKYVA SFVGFAPADD PQVAMLVVID EPVGLYYGGQ
IAAPVFGAVM KDVLQYLKVN PQLSANSQTG TEQAHVPVPS VINLSVPEAV KELQQAGLIP
RIEETGDRIA DQIPKPGSRI PSGGGVLLYT MTPRYSAGEV TVPDLTGRTL REASDSLAEL
GLAIKPVGTN GQAVKQDPLA GSKVLSGTSI TIYFE
//
