ID   A0A0U1NGY6_9RHOB        Unreviewed;       501 AA.
AC   A0A0U1NGY6;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Choline-sulfatase {ECO:0000313|EMBL:CRK74008.1};
DE            EC=3.1.6.6 {ECO:0000313|EMBL:CRK74008.1};
GN   Name=betC {ECO:0000313|EMBL:CRK74008.1};
GN   ORFNames=NIG5292_00031 {ECO:0000313|EMBL:CRK74008.1};
OS   Nereida ignava.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Nereida.
OX   NCBI_TaxID=282199 {ECO:0000313|EMBL:CRK74008.1, ECO:0000313|Proteomes:UP000048949};
RN   [1] {ECO:0000313|EMBL:CRK74008.1, ECO:0000313|Proteomes:UP000048949}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 5292 {ECO:0000313|EMBL:CRK74008.1,
RC   ECO:0000313|Proteomes:UP000048949};
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CVQV01000001; CRK74008.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0U1NGY6; -.
DR   STRING; 282199.GCA_001049735_00031; -.
DR   Proteomes; UP000048949; Unassembled WGS sequence.
DR   GO; GO:0047753; F:choline-sulfatase activity; IEA:UniProtKB-EC.
DR   CDD; cd16032; choline-sulfatase; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR017785; Choline-sulfatase.
DR   InterPro; IPR025863; Choline_sulf_C_dom.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   NCBIfam; TIGR03417; chol_sulfatase; 1.
DR   PANTHER; PTHR45953; IDURONATE 2-SULFATASE; 1.
DR   PANTHER; PTHR45953:SF1; IDURONATE 2-SULFATASE; 1.
DR   Pfam; PF12411; Choline_sulf_C; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CRK74008.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000048949}.
FT   DOMAIN          3..344
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   DOMAIN          446..497
FT                   /note="Choline sulfatase enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12411"
SQ   SEQUENCE   501 AA;  57487 MW;  EC9972A1B45D6C78 CRC64;
     MKPNILILMV DQLNGTLFPD GPAEWLHAPN LKKLAARSTR FKNAYTASPL CAPGRAAFMS
     GQLPSATGVY DNAAEFPSSV PTYAHHLRRA GYRTCLSGKM HFVGPDQMHG FEERLTTDIY
     PADFGWTPDY RKPGERIDWW YHNMGSVTGA GVAETSNQME YDDEVAYNAK TKLYEFSRGL
     DERPWCMTVS FTHPHDPYVA RKKYWDLYED CEHLEPEIPA MDYEDHDTHS KRIFDANDWR
     SFDITKEDIR RSRQAYFANI SYLDDKVGEL LQVLEDTRQE AIIVFVSDHG DMLGERGLWF
     KMSFYEGSSR VPMMICAPQM DAGLHETPVS NIDVCPTLCD LAGVSMDEVM PWTAGQSLVP
     MGQGVERTEP VAMEYAAEAS YAPLVSLRYG PWKYNRCTLD ADQLFNLEDD PHELTNLAED
     PAHQGTLQTL RAKSEARWDL ARFDADVRHS QAKRWVVYEA LRNGDYYPWD YQPLKRASEQ
     YMRNHMDLNV LEESKRFPRG E
//