ID   A0A0U1NP98_9RHOB        Unreviewed;       811 AA.
AC   A0A0U1NP98;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:CRK76548.1};
DE            EC=2.1.2.10 {ECO:0000313|EMBL:CRK76548.1};
GN   Name=gcvT_7 {ECO:0000313|EMBL:CRK76548.1};
GN   ORFNames=NIG5292_02612 {ECO:0000313|EMBL:CRK76548.1};
OS   Nereida ignava.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Nereida.
OX   NCBI_TaxID=282199 {ECO:0000313|EMBL:CRK76548.1, ECO:0000313|Proteomes:UP000048949};
RN   [1] {ECO:0000313|EMBL:CRK76548.1, ECO:0000313|Proteomes:UP000048949}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 5292 {ECO:0000313|EMBL:CRK76548.1,
RC   ECO:0000313|Proteomes:UP000048949};
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; CVQV01000022; CRK76548.1; -; Genomic_DNA.
DR   RefSeq; WP_048599957.1; NZ_CVQV01000022.1.
DR   AlphaFoldDB; A0A0U1NP98; -.
DR   STRING; 282199.GCA_001049735_02611; -.
DR   OrthoDB; 7156675at2; -.
DR   Proteomes; UP000048949; Unassembled WGS sequence.
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000313|EMBL:CRK76548.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000048949};
KW   Transferase {ECO:0000313|EMBL:CRK76548.1}.
FT   DOMAIN          6..364
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          368..421
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          430..699
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          724..803
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   811 AA;  89386 MW;  6A8D2946DAD8CD7D CRC64;
     MRDQARVVVI GGGIAGCSAL YHLTQEGWTD VMLIERDELT SGTTWHSAAQ VTNFGMSQTM
     VGLKTHSITL YKELRDDPEY PVGYNYGDGG IRLANTQAQM DGYRQFTSMA AGMGVEFEVL
     DAAECARRHP LISTDNLLGG LWDPTDGHID PAQLCQALAR RARLAGAEVN RHTPVTRLTQ
     HADSTWTVHT EKGDVRCEIV VNAGGYRCNE IGAMMGVQHP VASMEHQYFL TEDIPAIAEA
     GHRMPLLRCP ISDYYSRQEK GGLLLGFYEQ DCRTWGMDGI DPKFTNALCP DDLDRVTDVL
     EGAFARMPVL METGIREVVN GPITYTIDGA PLVGPIPGKR NAFCIIGLRA GLGEGGGHGW
     LLAQQIVHGE AQYDTWVIDP RRFTGHATVE LTALKAIEDY QNEFRFHFPH EHRPAGRPMK
     TTPLTQVLIS EGAEMGTVNG WERVDYIKPT QDFKETLGFK FNEVHDVVAK EVTAISTNVG
     MTEVSGFNRF ELTGTDVHSF LDRMMCGTVT KREGRVGLGY LLNNHGLLKA EATIANIPAS
     DRGPARVWYG SAAASEYHDM DWLKAHIKAD EDVKIRSLTN AQTILVIAGP KARDVLSMTA
     REDWSREAFP WLSVRETHIG IAPATVLGVS FSGELAYEIH VPNESLHAAY VALRKAGEAY
     GMTLFGSRAV ESMRMEKGFL HWKSDILTEF DPFETGLERF VQLSKGDFIG KDALEKRMVA
     GQQRKLVTLV IDAKHAPAHG GASVRLDGRI IGTVTSGDWG HRVDKNLAFA FIEPEFSPVG
     TTMTVDIIGE AFAAEVIESG PYDPEYSRIR S
//