ID A0A0U1RNG5_MOUSE Unreviewed; 186 AA.
AC A0A0U1RNG5;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 2.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=IQ motif containing GTPase activating protein 1 {ECO:0000313|Ensembl:ENSMUSP00000145556.2};
DE Flags: Fragment;
GN Name=Iqgap1 {ECO:0000313|Ensembl:ENSMUSP00000145556.2,
GN ECO:0000313|MGI:MGI:1352757};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000145556.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000145556.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000145556.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000145556.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000145556.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A0U1RNG5; -.
DR SMR; A0A0U1RNG5; -.
DR jPOST; A0A0U1RNG5; -.
DR ProteomicsDB; 318324; -.
DR Antibodypedia; 2891; 497 antibodies from 41 providers.
DR Ensembl; ENSMUST00000205813.2; ENSMUSP00000145556.2; ENSMUSG00000030536.11.
DR AGR; MGI:1352757; -.
DR MGI; MGI:1352757; Iqgap1.
DR VEuPathDB; HostDB:ENSMUSG00000030536; -.
DR GeneTree; ENSGT00950000183076; -.
DR ChiTaRS; Iqgap1; mouse.
DR Proteomes; UP000000589; Chromosome 7.
DR Bgee; ENSMUSG00000030536; Expressed in left lung lobe and 273 other cell types or tissues.
DR ExpressionAtlas; A0A0U1RNG5; baseline and differential.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR PANTHER; PTHR14149:SF15; RAS GTPASE-ACTIVATING-LIKE PROTEIN IQGAP1; 1.
DR Pfam; PF00307; CH; 1.
DR SMART; SM00033; CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:A0A0U1RNG5,
KW ECO:0007829|MaxQB:A0A0U1RNG5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 66..181
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000145556.2"
FT NON_TER 186
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000145556.2"
SQ SEQUENCE 186 AA; 21303 MW; C998819E8E4F6637 CRC64;
VGWSQVSGMS GIQGPGKQLR CQQRPMAELE GSLGGGVLSL AVLDNERLTA EEMDERRRQN
VAYEYLCHLE EAKRWMEACL GEDLPPTTEL EEGLRNGVYL AKLGNFFSPK VVSLKKIYDR
EQTRYKATGL HFRHTDNVIQ WLNAMDEIGL PKIFYPETTD IYDRKNMPRC IYCIHALSLY
LFKLGL
//
