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Database: UniProt
Entry: A0A0U1RQ35_MOUSE
LinkDB: A0A0U1RQ35_MOUSE
Original site: A0A0U1RQ35_MOUSE 
ID   A0A0U1RQ35_MOUSE        Unreviewed;        73 AA.
AC   A0A0U1RQ35;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   25-APR-2018, entry version 12.
DE   SubName: Full=SH2B adapter protein 1 {ECO:0000313|Ensembl:ENSMUSP00000146229};
DE   Flags: Fragment;
GN   Name=Sh2b1 {ECO:0000313|Ensembl:ENSMUSP00000146229,
GN   ECO:0000313|MGI:MGI:1201407};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000146229};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000146229}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000146229};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000213|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and
RT   expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000146229}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000146229};
RG   Ensembl;
RL   Submitted (DEC-2015) to UniProtKB.
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DR   EMBL; AC125322; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; A0A0U1RQ35; -.
DR   Ensembl; ENSMUST00000206643; ENSMUSP00000146229; ENSMUSG00000030733.
DR   MGI; MGI:1201407; Sh2b1.
DR   GeneTree; ENSGT00530000063355; -.
DR   ChiTaRS; Sh2b1; mouse.
DR   Proteomes; UP000000589; Chromosome 7.
DR   ExpressionAtlas; A0A0U1RQ35; baseline and differential.
DR   GO; GO:0005622; C:intracellular; IEA:GOC.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0035591; F:signaling adaptor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   InterPro; IPR015012; Phe_ZIP.
DR   InterPro; IPR036290; Phe_ZIP_sf.
DR   InterPro; IPR030523; SH2B.
DR   InterPro; IPR030521; SH2B1.
DR   PANTHER; PTHR10872; PTHR10872; 1.
DR   PANTHER; PTHR10872:SF3; PTHR10872:SF3; 1.
DR   Pfam; PF08916; Phe_ZIP; 1.
DR   SUPFAM; SSF109805; SSF109805; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   Proteomics identification {ECO:0000213|EPD:A0A0U1RQ35,
KW   ECO:0000213|MaxQB:A0A0U1RQ35, ECO:0000213|PeptideAtlas:A0A0U1RQ35};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN       25     73       Phe_ZIP. {ECO:0000259|Pfam:PF08916}.
FT   NON_TER      73     73       {ECO:0000313|Ensembl:ENSMUSP00000146229}.
SQ   SEQUENCE   73 AA;  7907 MW;  4331A3EF836ED179 CRC64;
     MNGAPSPEDG VFPSPPALPP PPPPSWQEFC ESHARAAALD LARRFRLYLA SHPQYAEPGA
     EAAFSGRFAE LFL
//
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