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Database: UniProt
Entry: A0A0U3KAZ3_9FLAO
LinkDB: A0A0U3KAZ3_9FLAO
Original site: A0A0U3KAZ3_9FLAO 
ID   A0A0U3KAZ3_9FLAO        Unreviewed;       474 AA.
AC   A0A0U3KAZ3;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   05-JUL-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AUW17_07945 {ECO:0000313|EMBL:ALU75199.1};
OS   Tenacibaculum dicentrarchi.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Tenacibaculum.
OX   NCBI_TaxID=669041 {ECO:0000313|EMBL:ALU75199.1, ECO:0000313|Proteomes:UP000061908};
RN   [1] {ECO:0000313|EMBL:ALU75199.1, ECO:0000313|Proteomes:UP000061908}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AY7486TD {ECO:0000313|EMBL:ALU75199.1,
RC   ECO:0000313|Proteomes:UP000061908};
RX   PubMed=26893432;
RA   Grothusen H., Castillo A., Henriquez P., Navas E., Bohle H., Araya C.,
RA   Bustamante F., Bustos P., Mancilla M.;
RT   "First Complete Genome Sequence of Tenacibaculum dicentrarchi, an
RT   Emerging Bacterial Pathogen of Salmonids.";
RL   Genome Announc. 4:e01756-15(2016).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP013671; ALU75199.1; -; Genomic_DNA.
DR   RefSeq; WP_058885343.1; NZ_CP013671.1.
DR   EnsemblBacteria; ALU75199; ALU75199; AUW17_07945.
DR   KEGG; tdi:AUW17_07945; -.
DR   KO; K02313; -.
DR   Proteomes; UP000061908; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000061908};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000061908}.
FT   DOMAIN      171    301       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      382    451       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     179    186       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   474 AA;  54196 MW;  0FDAA813B0A5A7C6 CRC64;
     MTKTADSVWK ECLSFIKDNI KHQAYKTWFE PIKPVKLAEE ALTVQVPSKF FYEWLEEHYI
     KLLRVALVKE LGADARLIYD VRLENTYSSN SPQIVKIPSS NRKAVKSPKT TVPTESKREL
     KNPFVIPGLQ KVKIESQLNP NYNFINYIEG DANRLARSAG MAVANKPGGT SFNPLLVYGP
     VGLGKTHLVQ AIGVEVKDKY PDKTVLYISS EKFTQQFIDS VKSNTRNDFI HFYEMVDVLI
     IDDIQFLSGK TGTQEVFFHI FNHLHQNGKQ VILTSDKAPV DMQDIELRLL SRFKWGLSAE
     LQAPSFETRV SILHNKLYQD GVEMPEDVIE YIAKNVKANV RELEGVIISM IAQASFNKRD
     FTVSLAREIV DKFVKTTQRE ISIDYIQRVV AKYFEMDVAM LQSKTRKRHI VQARQLAMFF
     AKRLTKLSLA SIGSQIGKRD HATVLHACKT VDNLTETDKK FKKYVEELTA KLTF
//
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