ID A0A0U3NVL7_9ACTN Unreviewed; 634 AA.
AC A0A0U3NVL7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=AS200_28045 {ECO:0000313|EMBL:ALV35467.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV35467.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV35467.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV35467.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; CP013743; ALV35467.1; -; Genomic_DNA.
DR RefSeq; WP_058925077.1; NZ_CP013743.1.
DR AlphaFoldDB; A0A0U3NVL7; -.
DR STRING; 1725411.AS200_28045; -.
DR KEGG; scx:AS200_28045; -.
DR OrthoDB; 3196263at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF59; DNA HELICASE; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 2.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT DOMAIN 10..634
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 31..38
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 634 AA; 71395 MW; F42712269BE7CD7C CRC64;
MTDVYQDSPP LTDEQLAVVE QPWDARVLVT AGAGAGKTHT LVRRLDALCG HEDPEQALEA
AEILVLTFSR AAARELRERI TRHGERAHRV RARTFDAWAY EVLLQAHPDG EWGAVGFDER
IAAATRAIEK GALEVGDAVP PVHVVIDEVQ DLLGGRRELV ETLLDRYQDS CGFTVVGDPA
QSVYGFQIED PGERLDETGR FFDWLRCSYL DDLVELRLTR NFRAATPEAR VALAHGPRLQ
QVTDPDEAAS VYDELRDLLV DPANGMAGLD DEFTLNSLRD LSDTCAVLTR DNQQALVVSG
LLHAHGIDHR LRRPLEERPV PYWVAELLRR TEATGLTEDR FRTLLSEIPL PYEPDATALW
TVLRRVARGV GRGVIDLDRL RRAVADGRFP DEAADPENTR IVVSTVHRAK GLEFDRVIVL
TPPTVAELHK RHRDELDLPA EARALYVAMT RARQDLYHVA PPELPHFKRA GSRRMGRRYL
GSWRSYDRYG IVAESGDVCR NDPPGRQGDA VATQAYLLQQ VRPGQKVLLR KRHDLPMSEV
ESPPYVLMHD GKEIGEASQR FREDLFQVQK VNRTWDPWWP DEIHDLRIDT LETVTGSTAA
GTNAGLGERG VWIAPRITGI GRFRRADDYE EQRA
//
