ID A0A0U3Q385_9ACTN Unreviewed; 310 AA.
AC A0A0U3Q385;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:ALV35539.1};
GN ORFNames=AS200_28475 {ECO:0000313|EMBL:ALV35539.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV35539.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV35539.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV35539.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
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DR EMBL; CP013743; ALV35539.1; -; Genomic_DNA.
DR RefSeq; WP_058925149.1; NZ_CP013743.1.
DR AlphaFoldDB; A0A0U3Q385; -.
DR STRING; 1725411.AS200_28475; -.
DR KEGG; scx:AS200_28475; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ALV35539.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT DOMAIN 16..283
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 310 AA; 32841 MW; 145C10B3EF551C22 CRC64;
MTLPMVVPAA GLPARVRIHE VGARDGLQNE KSAVPTEVKA EFVRRLADAG LTTIEATSFV
HPKWVPQLAD AEALFPLVRE LPVDLPVLVP NQRGLDRALA LGARRVAVFA SATESFAKAN
LNRTVDESLA VFDPVVRHAR DEGAHVRGYV SMCFGDPWEG AVPVPQVVRV CRALMDMGCQ
ELSLGDTIGV ATPGHVDALL TALDAEGVHA DVVGVHFHDT YGQALANTLA ALRRGVTTVD
ASAGGLGGCP YAKSATGNLA TEDLVWMLQG LGIDTGVDLG RLVATSVWMA EQLGRPSPSR
TVRALSHQEQ
//
