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Database: UniProt
Entry: A0A0U4AB71_9BACT
LinkDB: A0A0U4AB71_9BACT
Original site: A0A0U4AB71_9BACT 
ID   A0A0U4AB71_9BACT        Unreviewed;       517 AA.
AC   A0A0U4AB71;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-SEP-2017, entry version 15.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AUC43_10210 {ECO:0000313|EMBL:ALW85436.1};
OS   Hymenobacter sedentarius.
OC   Bacteria; Bacteroidetes; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Hymenobacter.
OX   NCBI_TaxID=1411621 {ECO:0000313|EMBL:ALW85436.1, ECO:0000313|Proteomes:UP000059542};
RN   [1] {ECO:0000313|EMBL:ALW85436.1, ECO:0000313|Proteomes:UP000059542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG5B {ECO:0000313|EMBL:ALW85436.1,
RC   ECO:0000313|Proteomes:UP000059542};
RA   Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP013909; ALW85436.1; -; Genomic_DNA.
DR   RefSeq; WP_068192704.1; NZ_CP013909.1.
DR   EnsemblBacteria; ALW85436; ALW85436; AUC43_10210.
DR   KEGG; hyg:AUC43_10210; -.
DR   KO; K02313; -.
DR   Proteomes; UP000059542; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000059542};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059542}.
FT   DOMAIN      213    349       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      425    494       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     221    228       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   517 AA;  58021 MW;  AD58974F39194D75 CRC64;
     MLKDFRTVWA GCLRSISAEI GEQSFKTWFQ PIAPVELKGN VLTIQVPSAY FYDWLEEHYV
     DELRRALFQE LGPDGRLEYS VVVDQGNEQT PPRSLHLPPS RKTSAPDPRD APQPMQSNVG
     NPLAGSGRAA SARYVNSAAV RTTPRGNFGI NNQSADTLAP PRNPFDTARP MDGNLVPSQL
     NGSYTFDNYI EGDCNRLARS AGLAVANKPG TTSFNPLMVY GGVGLGKTHL VQAIGNHIKA
     TAPERFVLYV SAEKFTNQFI DSVQRAQVQD FANFYLQVDA LILDDVQFLA NKGKTQEMFF
     HIFNHLHQSG KQIVMTSDRP PKDLQGLEDR LLNRFKWGLT ADVQSPDFET RVAIIRNKME
     QDGIDIPPDH VVDYLANSVH TNVRELEGVI ASLVAQSSLS RRDIDLEMVK QALRHIIEEV
     EAEVNLDFIQ KTVAAYFNIS VELLKDKTRK KEVVTARQVA MYFAKHHTAH TLKTIGFHFG
     GRDHTTVMHS VQTVSDLVDS DKKFREQVEE LRKKFAK
//
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