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Database: UniProt
Entry: A0A0U4FSZ0_9MICO
LinkDB: A0A0U4FSZ0_9MICO
Original site: A0A0U4FSZ0_9MICO 
ID   A0A0U4FSZ0_9MICO        Unreviewed;       464 AA.
AC   A0A0U4FSZ0;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-SEP-2017, entry version 16.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AB663_000858 {ECO:0000313|EMBL:ALX66009.1};
OS   Microbacterium sp. XT11.
OC   Bacteria; Actinobacteria; Micrococcales; Microbacteriaceae;
OC   Microbacterium.
OX   NCBI_TaxID=367477 {ECO:0000313|EMBL:ALX66009.1, ECO:0000313|Proteomes:UP000065197};
RN   [1] {ECO:0000313|EMBL:ALX66009.1, ECO:0000313|Proteomes:UP000065197}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=XT11 {ECO:0000313|EMBL:ALX66009.1,
RC   ECO:0000313|Proteomes:UP000065197};
RA   Yang F., Li L., Yang M., Guo X., Hou Y., Chen X., Li X.;
RT   "Draft genome sequence of a xanthan-degrading Microbacterium sp.
RT   strain XT11 with the potential for xantho-oligosaccharides
RT   production.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP013859; ALX66009.1; -; Genomic_DNA.
DR   RefSeq; WP_067196093.1; NZ_CP013859.1.
DR   EnsemblBacteria; ALX66009; ALX66009; AB663_000858.
DR   KEGG; mix:AB663_000858; -.
DR   PATRIC; fig|367477.3.peg.858; -.
DR   KO; K02313; -.
DR   Proteomes; UP000065197; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000065197};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000065197}.
FT   DOMAIN      159    287       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      371    440       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     167    174       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   464 AA;  51910 MW;  3A04E562898D8C21 CRC64;
     MSSPAQPDVP IWTTVQELLE ADDRVTPQLQ GFLSLAVPAG VMAATLYLEV PNDLTAAQIN
     KRLRLPIMEA LSHIGDEVTS YRVVVNHELA EQPTAPIAVP DYGRQDSARP ESPMEQQPTP
     IRHESRLNPK YTFDNFVIGQ SNRFAHAAAV AVAEAPAKAY NPLFIYGDSG LGKTHLLHAI
     GDYAQSLYAG VKVRYVSSEE FTNDFINSIA NNRGAAFQAR YREVDILLID DIQFLQGRAE
     TQEAFFHTFN TLHDHNKQVV ITSDVAPKLL TGFEDRMRSR FEWGLITDVQ APDLETRIAI
     LRKKAQSESL HIPDDVLEYI ATVVSSNIRE LEGALIRVSA FASLNRSALD ISLAQTVLRD
     IVDTAEDNII SPTDIITATA QYFKLTVDDL YGSSRSQQIA VARQIAMYLC RERTNLSLPK
     IGQLFGNRDH TTVMYAYKKI SDLMKERRSI YNQVTEITTQ LGRR
//
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