ID A0A0U5AWY9_9BACT Unreviewed; 688 AA.
AC A0A0U5AWY9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=THC_0727 {ECO:0000313|EMBL:BAU23118.1};
OS Caldimicrobium thiodismutans.
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfobacteriaceae; Caldimicrobium.
OX NCBI_TaxID=1653476 {ECO:0000313|EMBL:BAU23118.1, ECO:0000313|Proteomes:UP000068196};
RN [1] {ECO:0000313|EMBL:BAU23118.1, ECO:0000313|Proteomes:UP000068196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TF1 {ECO:0000313|EMBL:BAU23118.1,
RC ECO:0000313|Proteomes:UP000068196};
RX PubMed=26842785; DOI=10.1099/ijsem.0.000947;
RA Kojima H., Umezawa K., Fukui M.;
RT "Caldimicrobium thiodismutans sp. nov., a sulfur-disproportionating
RT bacterium isolated from a hot spring, and emended description of the genus
RT Caldimicrobium.";
RL Int. J. Syst. Evol. Microbiol. 66:1828-1831(2016).
RN [2] {ECO:0000313|Proteomes:UP000068196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TF1 {ECO:0000313|Proteomes:UP000068196};
RA Kojima H., Umezawa K., Fukui M.;
RT "Caldimicrobium thiodismutans sp. nov., a sulfur-disproportionating
RT bacterium isolated from a hot spring.";
RL Int. J. Syst. Evol. Microbiol. 0:0-0(2016).
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DR EMBL; AP014945; BAU23118.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U5AWY9; -.
DR STRING; 1653476.THC_0727; -.
DR KEGG; cthi:THC_0727; -.
DR PATRIC; fig|1653476.3.peg.750; -.
DR Proteomes; UP000068196; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR024521; ArsS-like_C.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR026351; rSAM_ArsS-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04167; rSAM_SeCys; 1.
DR PANTHER; PTHR43728:SF1; RADICAL SAM SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43728; SLR0304 PROTEIN; 1.
DR Pfam; PF12345; DUF3641; 1.
DR Pfam; PF13847; Methyltransf_31; 2.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000068196};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 392..612
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 688 AA; 78653 MW; 0A40B958D12E6F22 CRC64;
MAVESIVLET YKGAARSKEV KLCCPVSYTR PELLKIIPSE ILERDYGCGD PTQYVREGEV
VLDLGSGSGK HCYMIAQIIG PKGKIIGVDF NDEMLALARK YQQEIAKKIG YLNTEFRKAR
IQNLKLDLEK VDKYLLENPI KTFEDFIKFE EFIKYLEENE PLIPDNSIDT VVSNCVLNLV
RDEDKERLFK EIYRVLKPEG RAVISDIVSD EDVPEHLKKD PELWSGCISG ALREDKFLEA
FLKAGFISIK ILKYEEKPWQ VIDGIEFRSI TIEAVKGKKG ACIDKGHTVI FKGPFIRVED
SEGHLFELGK RVAVCERTFE NLKKYAYDFF IFIEPVKKLS PRPFPCGEKI IYRSPGVTKG
GKWETHSTKN TCCVQEEFKP FSEKLKELVI ILTKRDIEII QVNVGYRCNE RCLHCHLSAG
PKGQLMNDRV LSAVIELIKK HSGKTLDITG GAPELHPQIV DFINEVKPYT REILFRTNFS
ALLNKENLID FLAKKKVIII GSFPSLEEHK TDFFRGNGFF KKAFLALQKL NEAGFGKTLP
LYLMINPVEL SLTRKEEELR DEFINFFEEK GLSFTDLLVL NNFPLGRFKR YLQKQGKLKE
YYQLLYSNFN PETLNKIMCL KLINISPEGS LYDCDFNQAL KLKIKTPKNV FELLEVGLNS
LEGKPIQTGD HCYACTALYG TGCFGSLT
//
