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Database: UniProt
Entry: A0A0U5GPA5_9GAMM
LinkDB: A0A0U5GPA5_9GAMM
Original site: A0A0U5GPA5_9GAMM 
ID   A0A0U5GPA5_9GAMM        Unreviewed;       241 AA.
AC   A0A0U5GPA5;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-SEP-2017, entry version 13.
DE   RecName: Full=DnaA regulatory inactivator Hda {ECO:0000256|HAMAP-Rule:MF_01158, ECO:0000256|SAAS:SAAS00634471};
GN   Name=hda {ECO:0000256|HAMAP-Rule:MF_01158,
GN   ECO:0000313|EMBL:CUU24881.1};
GN   ORFNames=EM595_2650 {ECO:0000313|EMBL:CUU24881.1};
OS   Erwinia gerundensis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=1619313 {ECO:0000313|EMBL:CUU24881.1, ECO:0000313|Proteomes:UP000059419};
RN   [1] {ECO:0000313|EMBL:CUU24881.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=E_g_EM595 {ECO:0000313|EMBL:CUU24881.1};
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the interaction of DNA replication inititator
CC       protein DnaA with DNA polymerase subunit beta sliding clamp
CC       (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering
CC       DnaA inactive for reinititation, a process called regulatory
CC       inhibition of DnaA or RIDA. {ECO:0000256|HAMAP-Rule:MF_01158}.
CC   -!- SUBUNIT: The active form seems to be an ADP-bound monomer. Forms
CC       the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA,
CC       ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).
CC       {ECO:0000256|HAMAP-Rule:MF_01158}.
CC   -!- SIMILARITY: Belongs to the DnaA family. HdA subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_01158, ECO:0000256|SAAS:SAAS00548763}.
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DR   EMBL; LN907827; CUU24881.1; -; Genomic_DNA.
DR   EnsemblBacteria; CUU24881; CUU24881; EM595_2650.
DR   KEGG; ege:EM595_2650; -.
DR   PATRIC; fig|1619313.3.peg.2757; -.
DR   KO; K10763; -.
DR   Proteomes; UP000059419; Chromosome 1.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0032297; P:negative regulation of DNA-dependent DNA replication initiation; IEA:InterPro.
DR   HAMAP; MF_01158; Hda; 1.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR017788; Hda.
DR   InterPro; IPR022864; Hda_Enterobact.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   PRINTS; PR00051; DNAA.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03420; DnaA_homol_Hda; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000059419};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_01158,
KW   ECO:0000256|SAAS:SAAS00634466};
KW   DNA replication inhibitor {ECO:0000256|HAMAP-Rule:MF_01158,
KW   ECO:0000256|SAAS:SAAS00634468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059419}.
FT   DOMAIN       24    220       Bac_DnaA. {ECO:0000259|Pfam:PF00308}.
SQ   SEQUENCE   241 AA;  27268 MW;  F359EFDBDEC7F083 CRC64;
     MPALTEVILN TPAQLSLPLY LPDDETFASF WPGENPSLLA ALTGALQQEH GSYLYFWSRE
     GGGRSHLLHA ACAQMSARGE AVGYVPLDKR TWFVPEVLDG MEQMALVCID NIECIAGDDA
     WEMAIFDLYN RILETGKTRL LITGDRPPRQ LNLQLPDLAS RLDWGQIYRL QPLSDEDKLQ
     ALKLRANLRG FELPDDVGRF LLKRLDREMR TLFVTLDRLD RASISAQRKL TIPFVKDILA
     L
//
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