ID   A0A0U5KXH2_9GAMM        Unreviewed;       441 AA.
AC   A0A0U5KXH2;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=EM595_0605 {ECO:0000313|EMBL:CUU22842.1};
OS   Duffyella gerundensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Duffyella.
OX   NCBI_TaxID=1619313 {ECO:0000313|EMBL:CUU22842.1, ECO:0000313|Proteomes:UP000059419};
RN   [1] {ECO:0000313|Proteomes:UP000059419}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Blom J.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; LN907827; CUU22842.1; -; Genomic_DNA.
DR   RefSeq; WP_067427746.1; NZ_LN907827.1.
DR   AlphaFoldDB; A0A0U5KXH2; -.
DR   STRING; 1619313.EM595_0605; -.
DR   GeneID; 84614386; -.
DR   KEGG; ege:EM595_0605; -.
DR   PATRIC; fig|1619313.3.peg.631; -.
DR   OrthoDB; 5843984at2; -.
DR   Proteomes; UP000059419; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF4; PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059419};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        35..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        135..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        343..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        388..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..413
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   441 AA;  48130 MW;  D24516AEB1BDA153 CRC64;
     MSSLYLKLMS VIENHITPLA GAVGQQKYVT SIRDGFILAL PFMIVGSFML VFIFPPFAPD
     THWGFARAWL QFSLDHRESL MLPYNFSMGI MTIFISVGVA ASLARHHALD PLTSGMLSLM
     GFLLIAAPLK DDHISVAYFS GQGIFTALLV AIYTTELYAF FRRHNITIRL PPEVPTGVAR
     SFEILIPVLA VVLTLHPLNL FIESQLGMII PEAIMSLVKP LVAASDTLPA ILLSVLVCQI
     LWFAGIHGAL IVTGIMNPFW MANLSVNQAA MAAGSVIPHI YVQGFWDHYL LIGGVGSTLP
     LALLLMRSKA VHLRTIGRMG VVPGLFNINE PILFGAPVIM NPLFFIPFVL VPMINATLAW
     FALDLGWVAR VVSLTPWTTP APIGASWAAN WAFSPVIMCL ICMGTAIIMY YPFFKAFEKQ
     LLAQESSDAS APAVVGQSET A
//