ID A0A0V0QX22_PSEPJ Unreviewed; 1769 AA.
AC A0A0V0QX22;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ankyrin repeat-containing domain {ECO:0000313|EMBL:KRX06795.1};
GN ORFNames=PPERSA_11440 {ECO:0000313|EMBL:KRX06795.1};
OS Pseudocohnilembus persalinus (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Scuticociliatia; Philasterida; Pseudocohnilembidae;
OC Pseudocohnilembus.
OX NCBI_TaxID=266149 {ECO:0000313|EMBL:KRX06795.1, ECO:0000313|Proteomes:UP000054937};
RN [1] {ECO:0000313|EMBL:KRX06795.1, ECO:0000313|Proteomes:UP000054937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=36N120E {ECO:0000313|EMBL:KRX06795.1};
RX PubMed=26486372; DOI=10.1038/srep15470;
RA Xiong J., Wang G., Cheng J., Tian M., Pan X., Warren A., Jiang C., Yuan D.,
RA Miao W.;
RT "Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus
RT persalinus provides insight into its virulence through horizontal gene
RT transfer.";
RL Sci. Rep. 5:15470-15470(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX06795.1}.
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DR EMBL; LDAU01000091; KRX06795.1; -; Genomic_DNA.
DR EnsemblProtists; KRX06795; KRX06795; PPERSA_11440.
DR InParanoid; A0A0V0QX22; -.
DR OMA; NPRTLWS; -.
DR OrthoDB; 179808at2759; -.
DR Proteomes; UP000054937; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd19757; Bbox1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF73; INCREASED SODIUM TOLERANCE PROTEIN 2; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF04547; Anoctamin; 1.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054937};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 797..818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 824..845
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 900..924
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 944..962
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1242..1259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 523..555
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 781..1276
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
FT REGION 974..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1012..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1280..1300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1602..1627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 183..210
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1769 AA; 209787 MW; 7273AAC1BF50E6BD CRC64;
MKEKKIEEKK NPEKFKESIA LQNSQIIRNN SIQISDQNYD SGKKLVPQEN IDYEKQNQQL
QQQQEEQNQP DILQQINNLK GIKQQKSIEL LNNQQQKLGE SQLDQEKLEI DLDDEVDPIT
KCCKKLGDLL VCRDKDGKSF LGRFQFGQLT NIAGIQADLN RNKIPTVEDY VNKQDLFHNN
ALMIACIKEY QQLDNEVEQQ DENKEKNTQN QERLETIKQL VKNGADIHVR NPRTNWTPIH
WCAHHGDLES LKYLVEITKQ IENFEKGDSD DDEEIKKQQL INNTNPYQYQ INRLYEFGAS
YNEFLPDNEG KFPIDLAGKY NHVSVVRFLI ERTMKVIKEL NSYNKDNQSK KKQSLIKREK
YIKSPLYLHR CIFWACYHDM DQSFIQEFCE YSQDENIRIY VEAPLFYYHQ MTPIHCLSKL
QQNSKNNINT LNYFLKMRLT QGPFYNYLQN KCQKYTEKKH DFHIQFNSVL CLNNNPELKD
EEKVYKRVFI QEIKEFSLWE FNYIRNFNKG YNSKEYIDQQ DSFGNTALHL ACITNFTECA
DLLIEKNANP DTPNQEGWTP RELAQNIPKI KKIFLNKIKS QQIDHSVKVK KFEKEIKKSK
QFNQENEVEQ IKGGKEQKKQ EKIKELLQYA EKIFVPDFVI KFNTLGNKSA FKSKAEIKEA
INTQMNRMNL SMHHFLNEHF DVFLLKGIQE GVYYILVKGS DELLQKLCLH AIINQVTNLK
DQQKQKIIEK FYKMHTYGGI DRIKEQWIEN GKWYWPQPLN QMEAYLFKAK NTNFTALTYL
RQYLGEKISF FFAWKSFLTC TLVFLAFPGL FFQIYIIITG RWDHWFLPFW VFYVTVWNTL
IVEYWKRKSA EINYRWGNIQ IMGEHENQDE KKIRNDFVGD ECISNITGGL TKYQQKRKSI
FMFLITSPIL LLLMAAVVAT ILLVEWFKRN YKDKHQAYEL MAGGIQGISI VVLNFVYQLV
AVKAPRCVIK LQKPNKKKEA RQNLNNQKIK NKMDFTRAPN HRQNTLLTNK MEQSLQQKLQ
SQERLNTQNS NNADQEQQKF PIINNGNSKK HLQQQPLSLN LQQQQQNQQQ QLLQDINKKS
RTDMGTSKIS KNQLINNKNA ELESQSIDKQ LGVQQIKGCE ADSIELNSLR EQFDDMMIEP
YSDGFVDIGY ITLFAAAFPL GPIISLMANC LEIRIKLYQF MYVLQRPSCN DAQGIGEWLN
IWEYISFISI FTNFALLYFH DTDLFNQLLG EETTYDEGTK KLWVFLLTIT FLIFFRQALR
SIIIDKPKWV IEEEKKKHHQ QEKSRLQEEQ KQKQESSKFT KEIERVEKQY QTQIQQKNRD
LRDKKLELRE NEEKTKFMEK FLSKEFKDHL NTEKQKAQIK VKSKYFVDEF DRLYYGAIRS
TYTSIEREIL LKRIEQISQI NDQNLFICSN CSKQGAFIYC TKNYCDQIFC LDCFNRTHQI
DNHIKNLNDP SLSLPSKMKH TIRILKKQID YSRFLDHSIY SILNDDDGNN LYPSLPFKNY
FSEDLRNKNA DIKEYISQYS GQIQGIEQEI NSSIWKKFEY FSLPTFQQGA QHKNLKKFWQ
FFEDEYITEN GLNLEQKTVN IDKMLKFKAQ YKYTQDLDED NFDNHDNYNG DEKLNNKQKS
TDKTLKRQQK YIRQDSSTFQ NLLLEKDFNI EEKLFLNRIA FYTFKKKQNA QYSDFYQTCM
TLQDINAGNL IENALNKLYG NNKTIISKKE LFQKITQARY DNIDNKNENN SKKQLQEQQK
GENQTAEENC SQILAIIDSL VQVQIKQEK
//
