ID A0A0V0R9H8_PSEPJ Unreviewed; 718 AA.
AC A0A0V0R9H8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=GTPase Der {ECO:0000256|ARBA:ARBA00020953};
DE AltName: Full=GTP-binding protein EngA {ECO:0000256|ARBA:ARBA00032345};
GN ORFNames=PPERSA_05215 {ECO:0000313|EMBL:KRX11106.1};
OS Pseudocohnilembus persalinus (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Scuticociliatia; Philasterida; Pseudocohnilembidae;
OC Pseudocohnilembus.
OX NCBI_TaxID=266149 {ECO:0000313|EMBL:KRX11106.1, ECO:0000313|Proteomes:UP000054937};
RN [1] {ECO:0000313|EMBL:KRX11106.1, ECO:0000313|Proteomes:UP000054937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=36N120E {ECO:0000313|EMBL:KRX11106.1};
RX PubMed=26486372; DOI=10.1038/srep15470;
RA Xiong J., Wang G., Cheng J., Tian M., Pan X., Warren A., Jiang C., Yuan D.,
RA Miao W.;
RT "Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus
RT persalinus provides insight into its virulence through horizontal gene
RT transfer.";
RL Sci. Rep. 5:15470-15470(2015).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. EngA (Der) GTPase family.
CC {ECO:0000256|ARBA:ARBA00008279}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX11106.1}.
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DR EMBL; LDAU01000007; KRX11106.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0R9H8; -.
DR EnsemblProtists; KRX11106; KRX11106; PPERSA_05215.
DR InParanoid; A0A0V0R9H8; -.
DR OMA; IGTYERW; -.
DR OrthoDB; 5490026at2759; -.
DR Proteomes; UP000054937; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR HAMAP; MF_00195; GTPase_Der; 1.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR016484; GTPase_Der.
DR InterPro; IPR032859; KH_dom-like.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43834; GTPASE DER; 1.
DR PANTHER; PTHR43834:SF6; GTPASE DER; 1.
DR Pfam; PF14714; KH_dom-like; 1.
DR Pfam; PF01926; MMR_HSR1; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000313|EMBL:KRX11106.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054937};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 91..221
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
FT DOMAIN 434..553
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
FT DOMAIN 580..660
FT /note="GTPase Der C-terminal KH-domain-like"
FT /evidence="ECO:0000259|Pfam:PF14714"
FT REGION 692..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 718 AA; 83979 MW; 746022D6ACC87F45 CRC64;
MFKKLFNLQK ISQNNQKIAT ISKKQNYISI NLKQDTEKQG QLQYQCANYF CLRKNISNIK
YEEQFNQNKS YSQQKSKGQN LVTRKDDIFT VSLIGRPNVG KSSLFNKLSM GDYAITDATP
GLTRDRKETI TNILGFPIRI IDTAGMEREE IQQNDKHKNR NKFKRKQELI IGDKELRDKM
YNQTHQALIY SDLAIMIVDA KEGLTSQDYN IAQFLKKSIV QQKKKQKKLQ KIAEQKLAIE
GQNQHNNNQD VDIQENNQYN EENNTQNQEI ELFKNNKGFY NNEVMLVANK CDIQEVQDQI
INEAYQLGFG QPIFISCEQG DGLMDLLQLI KEKVPQSYEA AYEEKKLRRL EKHLKMRKSM
KQEIEQLIND GKIPDEFDIK EWEFEFDQNN LDVEENSDLD SDSEINIQEN LKLGINDDEF
YYNSQYQRKP IQLTVVGRQN AGKSTLANAL LKDDRVIVDD LEGTTRDSIK MQWVYQGRKI
DLVDTAGVDK KMKTRSEQSD LAVAQYIAEE GRALIVLVNK WDLVPAEYKK KAIRYMEKQL
ESKLSQVTGA PFICVSAKTG YNLEQVMQSV LLVHQKWDTR ITTGILNDWL NRFKKTQNAP
VTEGQILKIR FISQIRSRPP TFSIFVNDED LFKTNYLKYF RKSLVQEFKL EGVPIRFLIR
DSRYRKKMQK IKQKADPFDT INEAYKNKKD KIKQKKQDNF IKNNLNSSQE NQDELEII
//
