ID A0A0V0RNW0_9BILA Unreviewed; 629 AA.
AC A0A0V0RNW0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 {ECO:0000313|EMBL:KRX16169.1};
GN Name=PAPSS2 {ECO:0000313|EMBL:KRX16169.1};
GN ORFNames=T07_5930 {ECO:0000313|EMBL:KRX16169.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX16169.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX16169.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX16169.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Sulfur metabolism; sulfate assimilation.
CC {ECO:0000256|ARBA:ARBA00005050}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the sulfate
CC adenylyltransferase family. {ECO:0000256|ARBA:ARBA00009290}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the APS kinase
CC family. {ECO:0000256|ARBA:ARBA00007268}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX16169.1}.
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DR EMBL; JYDL01000113; KRX16169.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0RNW0; -.
DR UniPathway; UPA00097; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0000103; P:sulfate assimilation; IEA:UniProtKB-UniPathway.
DR CDD; cd02027; APSK; 1.
DR CDD; cd00517; ATPS; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.10.400.10; Sulfate adenylyltransferase; 1.
DR HAMAP; MF_00065; Adenylyl_sulf_kinase; 1.
DR InterPro; IPR002891; APS_kinase.
DR InterPro; IPR025980; ATP-Sase_PUA-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR024951; Sulfurylase_cat_dom.
DR InterPro; IPR002650; Sulphate_adenylyltransferase.
DR NCBIfam; TIGR00455; apsK; 1.
DR NCBIfam; TIGR00339; sopT; 1.
DR PANTHER; PTHR11055; BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE; 1.
DR PANTHER; PTHR11055:SF1; PAPS SYNTHETASE, ISOFORM D; 1.
DR Pfam; PF01583; APS_kinase; 1.
DR Pfam; PF01747; ATP-sulfurylase; 1.
DR Pfam; PF14306; PUA_2; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 234..388
FT /note="ATP-sulfurylase PUA-like"
FT /evidence="ECO:0000259|Pfam:PF14306"
FT DOMAIN 397..619
FT /note="Sulphate adenylyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01747"
SQ SEQUENCE 629 AA; 71547 MW; 96C2399D545AD0CA CRC64;
MEFPLQLFNV MIPARKRIRL ESRATNITPQ NHRVTREQRA QALGKYPNFR GCTIWFTGLS
GSGKTTISFA LEKVLCSVGL PAYGLDGDNM RHGICKNLGF SEEDREENIR RVAEVAKLFA
DLGIIALASF ISPFERDRRR ARKIHEDSGL IFIECFIDTP LEVCERRDPK GLYEKARVGK
ILDFTGIDSA YEVPENPELI LHAAEETVIQ CVQRVLQYLH ERGIFPDEAL MRLGGKVREL
FVDESERLRL EASLSQMPKL SLEKIDLQWL QVLSEGWATP LSGFMTETQY LQTLHFNQLI
EENTISQSIP IVLPVTSEEK AKLENADLIA LCYDGHTMAI LLKPEFYPHR KEERCARQFG
TCHLGHPTVK MIMQAGDWLV GGEVKTLKPI KWNDGLDQYR LTPMEIRQRL VEMGADAIFA
FQLRNPIHNG HALLMNDTKR TLISRGYKRP VLLLHPLGGW TKDDDVPLAV RMKQHQTLLE
EGVLDPESTL LAIFPSPMLY AGPTEVMWHA RARMAAGIHF YIVGRDPAGI QHPDTGDYLY
DPTHGSKILS MTPGLGDVEI LPFKVAAYNK RTQQMDYFDP SRKEEFDFIS GSRMRKIARE
GAQPPDGFMA PKAWEVLANY YRSLQNTVQ
//
