ID A0A0V0S7C2_9BILA Unreviewed; 591 AA.
AC A0A0V0S7C2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Histone H2A.V {ECO:0000313|EMBL:KRX22638.1};
GN Name=htz-1 {ECO:0000313|EMBL:KRX22638.1};
GN ORFNames=T07_9023 {ECO:0000313|EMBL:KRX22638.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX22638.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX22638.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX22638.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the histone H2A family.
CC {ECO:0000256|ARBA:ARBA00010691}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX22638.1}.
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DR EMBL; JYDL01000030; KRX22638.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0S7C2; -.
DR STRING; 6336.A0A0V0S7C2; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd00074; H2A; 1.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR002119; Histone_H2A.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR InterPro; IPR032454; Histone_H2A_C.
DR InterPro; IPR032458; Histone_H2A_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR14911; THUMP DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14911:SF13; TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3; 1.
DR Pfam; PF00125; Histone; 1.
DR Pfam; PF16211; Histone_H2A_C; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00620; HISTONEH2A.
DR SMART; SM00414; H2A; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00046; HISTONE_H2A; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleosome core {ECO:0000256|ARBA:ARBA00023269};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 59..192
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 591 AA; 65229 MW; 3FFA4C155CA3DF88 CRC64;
MYDFLNSKCY TFTMKHLRTF EGTVASGMEE IAILEVQAKL QCNLANKERG HIVFSISDDV
DAKKVLCLRS VNHINVVILD KAECSIENLE KGEALNNLNA LVQEACWNKG IEVWQSAVDG
GEASFKNESF VPKFRVSCQR SGGEHPFTSM EAASSFGGVV QAKFQWTVDL VNFDIEVIVR
ISGSQVRVSL ALTKKCLALR NLICFGSTTM KATICYGILY LCEIQNYEII CDPMCGTGAI
ILEAAHCWPK CILLAGDSNC RALKRCETNV KNFFTLQHST SAIISIQRWN ATKLPLTTGS
IDCIVTDLPY GRRSGSVRSN QTLYPALLSE FARVLKIGTG RACLVTNDKS TLTRSCMRVN
NYFDCRKLCH INIGGLYPAC VDLDYLKMLR IINLKILQLQ HEKRRTKNLF LILVCRRAQL
TLYLISMRIN LQSASSISDE AKYRLLVFIV TNVEMAAGKA GKDTGKSRTK AMSRSARAGL
QFPVGRIHRF LKQRTTSHGR VGATAAVYSA AILEYLTAEV LELAGNASKD LKVKRITPRH
LHLAIRGDEE LDTLIKATIA GGGVIPHIHR SLIGKKNPTV PGAPPTGGKA A
//
