ID A0A0V0SCD0_9BILA Unreviewed; 1633 AA.
AC A0A0V0SCD0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Tensin {ECO:0000313|EMBL:KRX24366.1};
DE Flags: Fragment;
GN Name=TNS {ECO:0000313|EMBL:KRX24366.1};
GN ORFNames=T07_1361 {ECO:0000313|EMBL:KRX24366.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX24366.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX24366.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX24366.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PTEN phosphatase protein family.
CC {ECO:0000256|ARBA:ARBA00007881}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX24366.1}.
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DR EMBL; JYDL01000018; KRX24366.1; -; Genomic_DNA.
DR STRING; 6336.A0A0V0SCD0; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR CDD; cd01213; PTB_tensin; 1.
DR CDD; cd09927; SH2_Tensin_like; 1.
DR Gene3D; 2.60.40.1110; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR013625; PTB.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035012; Tensin-like_SH2.
DR InterPro; IPR014020; Tensin_C2-dom.
DR InterPro; IPR033929; Tensin_PTB.
DR PANTHER; PTHR45734:SF10; BLISTERY, ISOFORM A; 1.
DR PANTHER; PTHR45734; TENSIN; 1.
DR Pfam; PF08416; PTB; 1.
DR Pfam; PF10409; PTEN_C2; 1.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00462; PTB; 1.
DR SMART; SM01326; PTEN_C2; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS51182; C2_TENSIN; 1.
DR PROSITE; PS50001; SH2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022912};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}.
FT DOMAIN 223..353
FT /note="C2 tensin-type"
FT /evidence="ECO:0000259|PROSITE:PS51182"
FT DOMAIN 1296..1403
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 393..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 695..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 975..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1633
FT /evidence="ECO:0000313|EMBL:KRX24366.1"
SQ SEQUENCE 1633 AA; 181462 MW; 3C461332E92E5E60 CRC64;
MLIIRKSVAR MRGGNGNLSS VQLVCCCPID FIYKVQHLHA VLPSPGNIMK SSQRTRNSKV
TRNNSCQPSS MLTFAFAGCD DLYSKSVQLT IKMLASKHDG KFKIFNVSKE RSELANLNVF
ECGWPECLAP ALEKLCTICK EMDRWLELST ENVVVIHQKG GFRRATVVVS AFMHYCSICA
SESQMLEHLA MQQYCKQHSL LPSQRRYVQN FANLLSERIQ VNSEPVVLYT LVVRGLTKRC
PVYFKIYGKM VPVFTSNVVS GNAAEVLVAR FRPPVSLRGD ILLKCCSAED EFHQKCTLFQ
CQFNTCTVNN HSCRKIVFKN DELDYPISEN LSLELFCAII EPNCKSEIYP TDDNGNNSSS
LLSFNTSNIE PVYLEPSTDN SFNSFEWFYD HNSSNEDGSK AEQQSSGGTT LAMRRRTATT
PPPRDADPIL EPDPDADLDV DHDRATEAGK DNGRKKRWLS RGSVESGRRD VEPALERPVV
VDVRGKRASF DVVTADSLGI VDVSPFRVGR AGVDRETRAP HWAPPQTRRV IDTNYGPFES
PFRPPAVVPP GKRAASPAPV RGHHARASPT VDKGDIDVDL VGEDRYDPQS RAFSYVPAQS
LEEHFRAPKK PTKLVPAFKY TDNWTVADEP LVAVEEDPAS ARVPNFDDLC DPNFYLNFDN
GRLSGTATES HNGAETDHHA LSLCTDVSVD CPIGDQGSNA WGADDNDPQQ QQQPAAEASS
KPSSTRHPST FHSNNYHSPL SAATLDSRWS PSPSSRGDFH FDDLTLGLEP LQTRRYQHRP
GQQLLLFDCS EPTTPRPFNN RCPSPNFYRN RQKLQVETRP VYTPTAWEER FLGGLGDQWD
DSQRVSMSRR PLYYGNSLPE WPAESDADSI SAGGPVDSES WLDLQMQKLK IRREVNDPTR
RRRREQERLL LEELKQVQHV DGGRGRFGRH GAVAGAVAGS KGAPLMDEST ASAVSSISNS
SPGRANEESH TITITNNNNT TTTTTPPHPG FTRRKTNNAN TTIPTSDHDT SPLLDVQSTV
GRNRDGLWSS SSSSHRHACY NPHQTNFDHC YYYSNTLSST KSASSPKSIL KKPKSFPAQP
FVSPSYQATE ELQSGNYYHD QVDGPDSSSY LKSRIDNTLA STDQPDYASS YMINSPARVE
TPAFPVRRME TPLPYHPLLY AGASTDDSRM MMSKVQNKPP PPPPPMSIRS LSPGSHYYAH
SVRSSLASLL ARMDGPRYIT TSSSSSSCSA CPNESNPTTN ITATTHYTTT ITPNAEIVDP
MSPLKMIDDL FTSWKTKTME VVHHHPVFVK DTSKYWYKPQ ISREETISVL KDKQPGSFII
RDSSSFPGAF GLALKVATAP PGVMTKGNSD GSELVRHFLI ETTAKGVKLK GCNNEPVFGS
LAALVYQHSI TPLALPCKLL LPDYDPAVSV EQVTTAQQLL EQGAACNVTY LYSNETESLT
GPEAIRRTID SALVLSSQKK IEPLNVHFKV SSQGITITDN TRKVFFRRHY PVQTITHCGL
DPENRQWCCN SNSGPARIYG FVARKSLAKS ENVCHLFAEL EPEQPASAIV NFVNKVIINP
NRSHVSSSFM AVVALKSLCQ LVTVHHHHHH QYPGDHRTSI AYLRMGEEAS SSRLVVFIDE
VKKKEKTNSS IYK
//
