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Database: UniProt
Entry: A0A0V0SN25_9BILA
LinkDB: A0A0V0SN25_9BILA
Original site: A0A0V0SN25_9BILA 
ID   A0A0V0SN25_9BILA        Unreviewed;      4270 AA.
AC   A0A0V0SN25;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   10-MAY-2017, entry version 10.
DE   SubName: Full=Ryanodine receptor 44F {ECO:0000313|EMBL:KRX28174.1};
GN   Name=Rya-r44F {ECO:0000313|EMBL:KRX28174.1};
GN   ORFNames=T07_2368 {ECO:0000313|EMBL:KRX28174.1};
OS   Trichinella nelsoni.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichocephalida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX28174.1, ECO:0000313|Proteomes:UP000054630};
RN   [1] {ECO:0000313|EMBL:KRX28174.1, ECO:0000313|Proteomes:UP000054630}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS37 {ECO:0000313|EMBL:KRX28174.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRX28174.1}.
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DR   EMBL; JYDL01000001; KRX28174.1; -; Genomic_DNA.
DR   Proteomes; UP000054630; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 2.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054630};
KW   Receptor {ECO:0000313|EMBL:KRX28174.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054630}.
FT   DOMAIN      103    157       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      164    208       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      218    272       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      278    339       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      344    402       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      582    817       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1045   1231       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4195   4230       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4233   4265       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4208   4219       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    4243   4254       {ECO:0000256|PROSITE-ProRule:PRU00448}.
SQ   SEQUENCE   4270 AA;  485611 MW;  F59E78E5E3E10750 CRC64;
     MTDFQENSTG EQDDISFLRT GDVVCLTCLA PCKESGTGSA ERVSLAAEGF GNRICYLEIV
     SDKNKPPDNA TSMFYIDQAL SVRALQEMMS SESPNISGSS STHRTLLYGH AVQLKHALSG
     MYLTCLSTSS ASDKLAFDVG LCETNVGEFC WWTIHPASKQ RSEGEKVRFG DDVILVSVAT
     ERYLHMSSTN GNTVLAAFHQ TLWSITPNSS GGVRERNMGY VCGNDVLRLN HGNDECLTIP
     ENWSDSPQNN IVIYENGKSC NQARSLWRPE LIHGKWQSSL IGWEQAFRIR HITSGRFLAL
     NEDNQVCLLH KDKASFESTA FIMISSKDVK RSTFEEKEEE GMGVATVKYG ETVIFLQHLQ
     SNLWLSCQTT AVTKKNMGKV EEKKAIAVEE ARMDDCFILF KAQEEESQSA RVIRKCSQIL
     NRFLRGLEGL QMEGKDSLAW NRADLSETVK LMEDLIQYFA QPEESVDFES MQNGLRALRN
     RQDLFQEEGL LNMIIDTIDQ FSAVESMTEL LDVTKEDKCK NWQDISTYLY LLVAAMIKGN
     HSNCTQFASA QRLNWLFSRL SNPQSAEGIL DVLYCILTES PEALNMINED HVKAVISLLE
     KVGHDPKVLN VLSALCEGNG VAVRNSQNVI CSELLCNKKF LLQTKMIDQV SSVMANIFVG
     SYENSAMYPR WYFEAELEYM ESMRTSGQKP HLRIGWASSA GYRAYPGSGK KWGCNGVGDD
     MFSFGFDGQC IYAGIAALKL SKLIGGIEKF VGTHEIRKGD VIGCSLDLAI PEIQFSLNGH
     QIGTSVRNFS SCDCLFYPVM SLSAIVSCRF FFGGSQGKLR FGPKKGYLPI SEAAITPVKL
     ISCISFGDTR KGYFAGPSTV ISDYIVFQPK PIDTKDVSLP KHLEDVHEKL AENIHELWAM
     DKIEKGWIYG ERRSETQKTH PCLTSYERLP TAERSYNLNL AKETLKTIVA LGYRIDIGKA
     SNRVKTFRLG QNFLMSNGYK PAPLDTREYE LNETLETLVD LLAKNMHNIW AQSKIQRGWT
     YSKNENVNIK TTSHLVAYDF LDPNIKAANR DKAGQIIRSL LVYNYCIEPP TAEQDEGAVK
     QSQVMNLQKR TYRFEKRYAV KSGKWYFEFE IRTSGFMNVG WMDVSASPDG DFGLHKSSYA
     YDGYLGRKWH GESESYGKKW NVGDVVGCFL DLTDRTICRL YVGFSLNGEL LLDSSGTEVA
     FDNVSAEDGF VPAFSLAPGQ IGRLNCGQNV NTLKYYTTCG LQEGYEPFCI RMSRQAPMWI
     AKYEAEFDEI NEQEKRFKVT RIPQSGDNPP CLKLQCKSAG MLERCSLALF RLNLPVFCKE
     ANDNRVCNQY FTETLSERNA GKRNCESDRI AESSRRGKMK GIRSSRNQDE NISFHDQHNY
     ADQYETSNHA VMKSNYLVQK TFSLDEDSSE VTENRFRKAP RLRSSASEAN LKEKESIDSQ
     DKISASYAVS NTKRNLRPFK VLQSFGQRMR DVSVGRSRKQ NARKLQEACA LKSKIRSDEN
     DKFPSGHLNS RKLDDRVADV DSTESLDMPK SGPGRRPTVI RLESDSKVKK RSNYFSSGHD
     LLVEASKLSA PSGNQHVSIG ASVSFYSTPD DYYFGVRVFP GQDLANIWIG WLTPQFSFTG
     SQIAADSQRI CFLESTHGTL DNIQEFRSCY IVNGMELLTA AGGSSNVSKM AGILAGCLIN
     TATGELKFHV NGKQTEMSYR VEPGTILYPA VFVLPTSREV LQFELGHIEK TLPIASAQLN
     ERSNAVQLMC PPRLKMEICK TRTWLRVPDQ CARVTSLKLS DTRGWSVLCD DLVRTMMLYV
     PERDSSIDIL ELAEHESLCT FHQQTLRLYC SLCAQGNFKI AHILCQHVDE DQLMYAIQSK
     YLSGSLRRCF YDVLIAIHLK CHYDARLAES HEYIIPLNAK LKDRNYFNYE TKSVYPHALN
     SDITLKSSIN VMEVKKKIST EDEKFLMSPT FDFHTLKQYV VDALEEATLE ALMNSRDLIG
     GTNTTHFLPI LKLFDTLLLV GVLSDKDIHR FFRLLNPKSF QETLDSPQNV KGLVDLDLDE
     MVQLELCHIM NHLCDLQLQG RVESLINFAE TFDQLRRYLE IKQTDMPSAE AARKTKEFRC
     PPKEQMLKLL DFKADRDEQT DEEGELEVSA MSEFLQRVLR EFHCNMVKFI GNSDKNDDNY
     STNVEQKQLE SENMNWVEKL AWMVVPVPPA LLSEDERIKF DGEEAFRNII LSTLIKWTGN
     KAIDDPNLIR EIFGLLLRQY TRISEMKSAL KTAYCIHERS IEDVQSFLDN LCQIRRLLCV
     QFEATEEEVL KNSLWDMMNN KVFFQHPDLM RLLKVHENVM TIMVNVLSRA QKSELDDRRN
     RSTQDDVKKA FQNSISDLVV ACCKFLCFIC RSSTKNQAAM FEHLPFLLDN ATMLLAKPSL
     RGSVPLDVAY YSFMENSELA LALKEDDLEK VAFYLSRCGL QANAEMVFKG YPDIGWDPVE
     GERYVDFLRF CVWVNGECVE ENANLVIRLL IRRPECLGPA LKGQGEGLFR AFKDAISLSS
     EINNLHKGRD LRSRFNFDLS HYPNPEIEEE DYIDLGAAIL GFYSSLADLL GKCAPDHLTV
     KSGKGESVRL RSILRSLTSV EDLEAILALR FLLPNVFAAK EESSRSSSIG LLPCHKQSIL
     LFLERVYGLI DKEMVFRLLE QSFILDFRAA TILDHPAYAE SDLALALNRY LCGSVLPLLT
     SHAHCFADAE HYYSLLEATL HTVYRMSKIK SLTKSQRSAI TEFLLAFTKE IHPGMMKKLL
     QKVVVDISSL NEFATVPLQI MTQHYECFSK HYGISMHEDT ASEEQKRLSM LLFTTIFDSL
     GKRAFDSDLF ASALPCLTAI GSALSPDYAM QSYAEEEIQN MNVPSGHMEV WRPHPVDASN
     VQLSVNLQNL VQRFAQHFHD SWASRKLEKG WRNDDIYSRT NCTHPRLKPF GMLKEFEQNF
     YKERCSECLK ALLAWGYSIE QETQVSSVQP KSMNPTSNVR SASVFCPQPI DLSNMTLSEE
     MCELAERIAE NSHLIWVSKT IEDLNDANTG IMVLLVPWDI LADSEKRKHR FRAQEVLKFL
     QYQGFRLKSP LHRAREEYQQ TVVDSNTHRP VEKRFACNLL EKLLAYLENA AQKMEVIKPS
     KQFSRYRNYT LPSEDVKFFG KVLLPLLESY FRSHRNYFTT ASSASLSGVA SIKEKEMVAG
     LFHRLMSVFR SKHNAFGCHV KSTVRCLQVL LQAIDFRSLV KINSDTLRTC AQIFLSNMVS
     DLMNITKEIK NNGRYAEIKG KTLPCTSSLL FLYEAMLPLL TTLFCHLSKH GHGQDFLVND
     IQVGCYKIAD CLYMLASPIT ISRKSVKEEM EKHRSSIGQC LSAFACCFPV AFLEGDFNLN
     SRGSTVDRQH LLSESKDTSS SLLLNIPSLD NLLSNIEQLS NTNGKYQDAP AIFDVDIPML
     CSYMSFWWQH GPTNNTQEKN LSAVSSDHIN RLFSACSRLI CDHIGIAHAD WICHLAPFIT
     PMINYVTIEP VRDYLLPMAE KVRMQADLAF KEEEKHRMHP DVFDESTVIE LHSILIRDVY
     ALYPILIKFT DLHRARWLKN PCWETNALFE HVAFVFKLWS TSQHMKREEL NFITQFESDF
     MTGTSRKTGK AAVAFRKKKR REGKRREKDS GSIVVACLKR LLPVGLSVFG GRELDLLQKV
     KEKYMKKEND EKIKEYISSS LAVPDQEDVF DKSHWQRKLY QQIGKAQMLG IDSMSQEMVV
     DKIIFMGVTL CNLHNVEHPQ TFQADAWRKI VSSQRKRAVV ACFRMVALYS IPKHRCVNLF
     LSAYIEKWLK SEKVDEDLLI SEVTVASEGR MQRLREDVEE VDEQCPPDPL SQLVQCFQRA
     ATSERKQLVP IVDDNLYIKY VRVMASSIHI NDDEQNNAED DAISMEAQEL EKQQLLHEQS
     RLADRGVAVM VLMYLSACNG EPNVMVEKTL ALGIHILNGG NSDVQNIMLN YLQEKKDVRF
     FSSISGLMNR CSVLNLEIFE RQLKAEGLGM GAELSVGKHQ NLNDSEFICS LFRFIQLTCE
     GHNSEFQNYL RNQPGNTTSI NLIICTVDYL LRLQESIMDF YWHFSSKEVV DEAGKAHFLK
     ALSVCSQVFN TLTESIQGPC VGNQMALANS RLWDAINGFF FLFAHMMDKL SKNHTQLELL
     REFLSLQKDM IVLMLSMLEG NILNGSIGKQ MVDTLAESQQ NVQLILKFFD MFLKLKDLTT
     SQAFQEFDTN KDGWISPKEF LRAMEAQKMY STEEINYLMM CTDVNNDGKI DYMEFTERFH
     NPAKDIGYIE
//
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