ID A0A0V0TU70_9BILA Unreviewed; 1087 AA.
AC A0A0V0TU70;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=NOP58 {ECO:0000313|EMBL:KRX42543.1};
GN ORFNames=T05_359 {ECO:0000313|EMBL:KRX42543.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX42543.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX42543.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX42543.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}. Secreted, extracellular space,
CC extracellular matrix {ECO:0000256|ARBA:ARBA00004498,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX42543.1}.
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DR EMBL; JYDJ01000142; KRX42543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0TU70; -.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd13113; Wnt; 1.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF1; NUCLEOLAR PROTEIN 58; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00931; NOSIC; 1.
DR SMART; SM00097; WNT1; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
FT DOMAIN 333..455
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 572..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..655
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..706
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..759
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1087 AA; 125233 MW; 9FAAC282EE31D37F CRC64;
MTLKCSLMEI LGYGLMCRLD DLFIAVEIIS LFKTAIVLDF ARQLQWHRRM LLLYETASGY
AIFRISEKFN LTKVDDLWSE FESPDKARQF VQLVNFRKFS DINQSLKSTM DIMENKCSKT
LKKVIKKFVL PEIQEKLAVA DAKLGNLIQE KFPGISCLSN SKITELFRGV RSNLNALLVD
IPRRELENMA VALAHNMSRH KLKFTAEKID MMIVQAIGLH DDLDRELNNY AMRCREWYGW
HFPELGKCIS DHLLYAQIVE RIGFRECAPM TNLSDLLSED LQKKVKKMSL HSLGTEISTT
DLKSIKLLCK QIIEISKYRT ELGNYLRARM FSLAPNLASL TGEIIGARLI ARAGSLLGLS
KMSASTIQII GAEKALFRAI KTKRDTPKYG LIYHAQIIST VPQKLKGKVA RMLANKATLA
VRYDALSEHT DDGDMNILGL EQRAILEKRI KALETEIAHQ VTKTKKVRFR EAPYIIQGGG
ELYDTSADFT LPRKRKHEND NASDFIETKK LKLTSILKDE KKERSKKLTI QGHQLAEEAQ
GYKVDKKMKK EKHLKEESVF MEQPAVESFV EQEEMVESSK KKKKKKKRTS DSADITLESV
EALGEIKTEP QLEIVEDVNV KKKKRKRKSG EEIESSEKKI TVKEEREKEE KRKDDDDKDE
EEDSDLKNLS QELSVKSKKK KKMKKQQIEE EYEAKEEEEE QQHLYGEDEG EESKLNLSTQ
STEKKKKKKK KKKNDSEVEQ WSFSNKKNDD NEAHMLPKSL RRQHFKDAWP RKEEACAPEI
LSIRRNRQLF VLCRHRPVLA KSLLSGLKEA VRECQFQMKH NRWNCSFGYH SMDYTLLDNP
PILNFGYKET SFLVALSSAG AAWSVARACA NGQLTSCTCN NRQHSSQQAW KWGGCSYSIK
FGLVNSRRLL TSKHSIHKAN LLKLVYKHNL KAGRMALKRT LKRDCKCHGI SGSCQMKTCW
KSPAEFREIG THLKKKLSRA MFILQNHSPN DSRYIAQQLK AAELVYFEQS PTYCEPLSHI
RSVGTRGRIC SVRNQTHSFA DCEIVCCGRG YFHQAELVVE NCNCKFHWCC QVMCDKCRRT
NWISKCR
//
