ID A0A0V0U206_9BILA Unreviewed; 1940 AA.
AC A0A0V0U206;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Myosin-3 {ECO:0000313|EMBL:KRX45306.1};
GN Name=unc-54 {ECO:0000313|EMBL:KRX45306.1};
GN ORFNames=T05_11728 {ECO:0000313|EMBL:KRX45306.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX45306.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX45306.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX45306.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril
CC {ECO:0000256|ARBA:ARBA00004657}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX45306.1}.
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DR EMBL; JYDJ01000078; KRX45306.1; -; Genomic_DNA.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0030017; C:sarcomere; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 3.
DR Gene3D; 1.20.5.370; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 27..76
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 80..760
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 635..657
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1889..1940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 824..1406
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1902..1940
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 173..180
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1940 AA; 224554 MW; BB0B33FFA37CF3D9 CRC64;
MTSVYEKDPA WKFLRQPVDL SKAKKYDSKK SCWIPDAQEG YIAAEIKSTK VDQLVVITEK
GLEKTVRKEE TQEMNPPKFD RTEDMSNLTF LNDASVLHNL RQRYYSMLIY TYSGLFCVVI
NPYKRLPIYG ESVVHMYQCK RRNEMPPHLF AVADEAYRNM MQDRGNQSML ITGESGAGKT
ENTKKVISYF AVICSTHANK EKDGKKRASL EEQIVQTNPV LEAFGNAKTV RNNNSSRFGK
FIRIHFNGHG KLAGADIEHY LLEKSRVIKQ AQGERCFHIF YQIMSGKIAG LKEKLFLSKD
IRKYKFISQA EITIDGVDDK EEMQITDDAF DIMNFDPSEK ENLYKLCAAI LHMEAELAAK
LLCVNCDEFL KALLKPKVKV GTEWVNKSQN LEQVTWGVGA LCKAIYARMF RWLILRCNRT
LDVQELGRKF FIGVLDIAGF EIFDFNSFEQ LWINFVNEKL QQYFNHHMFV LEQEEYKSEG
IAWEFIDFGL DLEACIQLIE KPLGIISMLD EECIVPKASD MTFVQKLNDQ HLGKHPNFQK
ARPPKGKQSE AHFSIVHYAG TVRYNANGWL EKNKDPLNES VVNVLKASDG NKLLSEVWAD
YFTQEDLAKK KTTPSKKKGK AASFLTVSMM YRESLGNLMS MLRATHPHFI RCIIPNESKK
SGIIEAGLVL NQLTCNGVLE GIRICRKGYP NRLVYADFKQ RYAIFAADEA KKYDDPKKSS
EAILNTLKQK DVLKAEEFQV GATKVFFKAG ILARLEELHD EELSKIMVGV QATARSYLAK
LDSRRRKKAH EASLLIQKNV RKWLKLRSWS WFRLYGRVKP LLTQAKQHEE FEKIQAKIKE
LEAASSAEKA RCADMEAQLA NALKEKSDLI LKLESEKSNS TEYEQKAKTL SSQMDDLNKQ
HKNLHEKLEM AEEQHSNTQK AKKKLQEEVD KLTARIVELE LLVKKHESDK QSLDMQLRSL
KDAALHQEDA HAKLSKEKKA SDDKVQKLTQ DLHAVEDKVV SAEKVNKKLE NSLEEAHDAL
EREKRLRQEL EKAKRKTDGD LKVTQENMEE ILKLKQDLEM NVKKKEDEIS VLNHTLEDEQ
STAVRLQKVV KDLQVRVAEV EEELNMERQN RNKIERRRKE LQDEMDELQQ QLEEAGGASQ
AQMELNKKRE AEIAKLKREQ EEAALAHEAQ ISSLKKKHTD AVAELNEQLN ALQNSRIKLE
KGKSVLQKEI EELHLAVDSE TKSKAVHEKQ VKSLEAQLVD LQTNHEETLR QLKELELQKS
RLVNESTDLQ KQLEEQDVQL NNLLRAKQTL SAELERTKQS CEEEMKQSES FASQLRNVQE
ELSSAKEQLE EEAEIKTELH RMLSKANAET QQWRAKYEQE GLRKTEELED AKKKLVIKLQ
SMQEEIEAAN LKANSAEKLR QRVVAELEDA VADSERANGY AQSLERKQRG FDKILDEWKQ
KCDDLSAELD SSQRENKAVV TELYKLRQAL EEATDREEAV RRENKMLAQE IQEINDQLGE
GGKNYHEVQK TRRRLEMEKE ELQNALDEAE SALETEENKV MRHQIELVQV KQEVEKRLQE
KEEEFENVRR NHAKALESVQ ATLEAESRGR MELMKAKKKL ESDINDLEIA LDQAAKGNVE
AQRLIKRYQE QIRELQAQID EEQRLRNEMK EKCESVERKC HALCAEKEEL TAMLEGSDRA
RRNASHEVHQ AKEQVNDLIV QLNAAIVNRR KLEAEYQLLQ SEMEEMMESS KVNEEKSRKA
TLEAVRLSDE LKQEQDHCQV LEQRNKSLEQ QIKDMQSGLE EAELSVLKGN KKYSQKLENK
IRDLEMELDI NQKKYQESEK NRRKSERQVK ELQYQVDETK KNEDRLHELI DKLQNKVKTY
KRQIEETEQL ASLNLSKYRQ LQHQLQDAEE RADVAENSLA KMRAKNRSQP YRSSSTIASP
RDLSKCRSLS ALNNSTDEES
//
