ID A0A0V0UE40_9BILA Unreviewed; 3520 AA.
AC A0A0V0UE40;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=WD repeat and FYVE domain-containing protein 3 {ECO:0000313|EMBL:KRX49313.1};
GN Name=WDFY3 {ECO:0000313|EMBL:KRX49313.1};
GN ORFNames=T05_7700 {ECO:0000313|EMBL:KRX49313.1};
OS Trichinella murrelli.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=144512 {ECO:0000313|EMBL:KRX49313.1, ECO:0000313|Proteomes:UP000055048};
RN [1] {ECO:0000313|EMBL:KRX49313.1, ECO:0000313|Proteomes:UP000055048}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS417 {ECO:0000313|EMBL:KRX49313.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX49313.1}.
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DR EMBL; JYDJ01000018; KRX49313.1; -; Genomic_DNA.
DR Proteomes; UP000055048; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd06071; Beach; 1.
DR CDD; cd15719; FYVE_WDFY3; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46108; BLUE CHEESE; 1.
DR PANTHER; PTHR46108:SF4; BLUE CHEESE; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000055048};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 2497..2624
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2652..2945
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 3105..3146
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 3448..3508
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 15..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2405..2464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3347..3372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3520 AA; 392994 MW; 33D8F4522E5200CF CRC64;
MVRKFSFVGA NEKSTSAQCN GASSTTENKN ASTSGATCNA SDSEKSSDHI LTLMHLRKVL
NELLRSANSS EDRDRKLYPV IRLFMKVCKV FTVEEITNRF KEAAQFVSLI SNLLVQEIRI
RAACPSTALP LTTLETALSV EAVCLLASGN RIEAAVEIVA YLKPTSDCSE TKVSGWSMLY
SLSFLLSSNK NCIVESACKT SLPSTLVKSL YLFCDLPKTC PLDEDQVRTL RGTLMKTMTV
MLRNPRGIEQ MASKDDLVLL FCGVSSWCPV FNHTWRNCSA ELLMTISSGV RSLLLINYIH
THKCIELFVD NLKHSTQETI PDMVEMICCL LCILKDFASV SSLLLDDFEN ADGYKFLGDL
VLQYENVQRQ NEQDSLRNLL FLVNSVVSAG CDEIKLPEVQ NPWKTSRPFH MPQPLGEGRT
VRNMKAFELL ETVFIHSRQT YICCTILDVL YSMLTADPVN YFILENRCPL GKFLETLSTK
SLKVQRKLFD LIEYVVFQLN YLPSKEFIAI GPVLKMNKDM ASIHLILGSL FKILTYNPAV
KDVFREVGLL DVFITVLQNV YTSVKSENEP NEQLWDTFTL TINTLCLLVK QCNANVVLVR
EIGGTKTVFA MVEDDCCRPL ALKLLQHIMM NPSGEDELAG VLALLHSPTD NPISLKSDVL
QFLSFVLRES HRVRMAFRRV GGYVYLLSLI LNMGGTFKNL KKDFQHTDSF FENFSYLRNI
FKVLTMSMRF EPSNAMFFQN EVKFNSLTDS LHLLGCFSEK RSFSVIPVKK GIAELRVDFL
STLCDIFNVA ADEKLSFPEG DLSENVVVIC AILRLLYDMA FDRSDRNGKV IEFTSEQPAH
SPNMISYRFA SLIGQNAFVV HTGAVMCMFE LLLYVEQPNP METLNVQLFI IEMVKSILRT
ERNQQVMCCV GLPRLLFDTV SDVFFEEEHP LLPPSYYILE RLAAQGMTPN ELRSFLRLDK
PWCCADLDSD EPSGSNVVAL NRVKTLVSMM TPKDLRLSLL NASPPFVEFD MSIEGFGCIF
LPSIAPVGFG FVTGGLPLMH SNSQDGAVMN RGGLGNGERI FPPLAGLTYL CWVYVERFSE
SGADAHPLRL LTVYRTLASS HSHVGQPCHH QSRSLEPSTP PTLQGNSEIA CLQMQISPVD
RSLIIATYET DTPGADLDKD VGSADGFVRL GIEELRRDRQ WNHLAVVLNR SVLKSSTVTV
YVNGQQKASQ RIQYVSHWPT MGTGAVASSL TTPQTCTVNA LIGTAPGPFR KQSSLLWRLS
GAYLVEEAMS SQAVGQAYEL GPHYTGSFQS PSSFLGRPMA SLVTEERVSF GLHATAMSTM
TLARLRKIYN KQDSRAIGKL LGISSHENIT PVRLIHNSTV HLAGPARTLG GVLVGYLGMR
TFCAKSSAKL LETVGGIACV LGLVSMADDT ESLYAAIKAL FFALKTNRAL NSEMEKIHGY
QILTVLLKEK SRFLNTHVLY LLFSMVGTLD VTRETVVIPN TQAFEDLFCD LQVWNDASVD
LQRLLYEHFY QLITESGSHE ENLAIVRHVG LLPRLLYTLA YQPHLLKATK DVIFNLISAI
LQPIADYTSL LKFGQFIIAT LQIKETSNIE KSLPNDIQDL QALLFNEDVE AEVDAATMRI
AYLVYIRNRC LNILLNMLLN TSGKLNFQLC EQICKVLGFD WILALFYGSN HKGTVRAGLQ
ILLTIAKHST LLNRFKEGVG NGGWLTDAES VVQNRAGVLL GFSVSARGSS VGSSCDLNLE
ICNLAGFVAL QYLLPGHASL AETQIACASL LVGHSARHLP TAHAQNVESI WSLIFNNAGD
QAVVTGAMGK LDLCPEASLP LLSVVRACVV SNEFARTECS EQNAVTLIQF VAFLYQNNSE
FSNYAQTSDF VVALASTLLR PNSKCRNNIE EETVRFTLPN HPAVRHVLEL LSSIAIDGFL
SGQPNKHESV IDILLGPVQQ NTNTVEEFRP LVTAFLLNTM DRLEATDVLA RGVGVPMCSP
AAPCTNYSIL AANIFYFAGK VVYCLWNDLF DGDSQSVFEF ILKLFAQVKR KSGPGVPLDA
LYSSWNRCIL FLLSRVLDDM KAQRTVVECL QKITANRALL FSTANGEPEF FCCLAHLLFM
LSDVGGLQPQ HKLDNETEKE EIEQRRLYDG RKLVSANAKR VWEELFLAKK QLLEETLGVT
IMPDVGASRA FASAAASQQW LNFVDNEMKG CYGAKDALQI HIQLQSKLHM VTGGLQRLAS
KKNIKSTGTA RQTVVSKQEF MMWLKVHVTL IHELFDLQYT RYLQWHEHTK KWCLDEWTNL
KQELTRERGL WGPKNPSVLN KYMLDSTEGP CRMRMKMIPN INFYVDYPYR PNVMNLENKM
TKNKLPCSSD SQLYYERVKT RHGSCFDPRI IDLSQPNSSK LEEGVQFDDA IVDVNAQMIK
NTIKRSATSV SSADGDRDEA NGTASSSDEP ISINDDVAVD DTASSSVFSD SPQARPRDGS
SFSSSTLCSS ASVASEQPER LFLPKEPDSQ TLLRLLEEGE ELNSMYRCAR ICGLDSSEGL
LLFGKYHYYV IDGFTLLKTR EIRDLDFLPE ELHDPIVPYI ASGATRNRSQ KRLCSKFAYE
DIRECHKRRY LLQPIAIEVF SSDGRNHLLA FPRKIRDKIY AKLLACAKSL TDAGHQSVSG
QKSGVDVEQG AGLLAVLMGE MSVTQRWVRG EISNFQYLMH LNTLAGRSYN DLSQYPVFPW
ILSDYDSEEL DLTNPNTFRD LSKPMGAQTP ARLEQFLKRF REWDDPSGET PPYMYGTHYS
SAMIVVSYLV RVEPFTQQFL KLQGGHFDLA DRMFHSVKDA WLSASRNNMA DVKELVPEFF
YLPNFLLNSN HFELGVKQSG LRLGDVILPP WAKGDAREFV RLHRQALESD YVSAHLNQWI
DLIFGYRQQG QAAVDAFNLF HHLFYEANVN FEAIEDPLTK NATIGFINNF GQIPSQLFKK
PHPVKRSLKS TLPLQHSISS NAACAVAQQG VEGPTAAGPL FYHVAENLKP PLQPLRELKQ
AVGHMAQNDK GALLAVEQNK VLVPPQFHRY LAWGFPDNSI RLGSSDFDKS VCIHESPHWG
DVICASCPNA HTAVTGSTCS VVCVWEIVGA ASRNQPAHLE LRKRLYGHTE PVSCIYASTN
FGVIVSGSRD RTCIVWDLSK LSFIRQLGPH AGPVSAVSVN EATGVIASCS GTHLHLWSFD
GQKLAWVNTA DSCKKSDMNE IIITITFSLL NEWDSQHVVA VGTNTGIVKL WTVKFVKVFD
DCSHVGRISS KSSSRSYCAL FAAEPDRDSH CDMDHVAVEA VNAFSNNDHC DGLTNDKVSF
TLGNSNNSHS SEDDEQDSDA AFVDEGVSKV LPTSSCAEVV QSRNSEMVDI RRRSSESTMQ
KSSEGANCCG DGEPQRKFHW ERQLVFRGKL TMHTAFERKD NPAPAAVTAL MPSKDHKALY
VGDGRGRVWM WTVGDGHIGG RADHWVQDPS RNLCSNCHQK FTLTDRRHHC RNCGQLFCSR
CSRFESEIRH LRIRRPVRVC QSCHARLKAT DDSQSSNHAS
//
