ID A0A0V0UW80_9BILA Unreviewed; 950 AA.
AC A0A0V0UW80;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000256|ARBA:ARBA00018307};
DE EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
GN Name=opa1 {ECO:0000313|EMBL:KRX55512.1};
GN ORFNames=T09_2039 {ECO:0000313|EMBL:KRX55512.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX55512.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX55512.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX55512.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.5;
CC Evidence={ECO:0000256|ARBA:ARBA00001837};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004434}. Mitochondrion membrane
CC {ECO:0000256|ARBA:ARBA00004325}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX55512.1}.
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DR EMBL; JYDN01000143; KRX55512.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0UW80; -.
DR STRING; 181606.A0A0V0UW80; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR045817; OPA1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF67; DYNAMIN-LIKE 120 KDA PROTEIN, MITOCHONDRIAL; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF19434; OPA1_C; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..950
FT /note="Dynamin-like 120 kDa protein, mitochondrial"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006870332"
FT DOMAIN 268..544
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT COILED 202..236
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 950 AA; 108678 MW; 7698C3FF3007BACE CRC64;
MRRIYCLFMR HVCLVSALRK SSPCFNVSSS QRGYVICRHS SLNRQVMSLL KVNVPLSVAP
YGIRNFSLIT RLVKGIMHIR YVVIGTIVGG GLTLSQHVQS WMDKLPDLSW INMDSTLVAQ
LKDSFRTVAD TVTTQKMLLY KKMEDTGWLP KQVKRDLLEW FEDKKTVLTD TPLLSLITDP
AVFVYAEESP SDEAKEAHER GRNDTLQTEM KFQEKIEQLE KENAELRRVL QSQSGKDVKL
RKGNESLIDM YSSVLDLLID YDSSYSTQDH LPRVVVVGDQ SSGKTSVLEM IAQARIFPRG
SGEMMTRAPV KVTLSDGPYH IAQFRDSQRE FDLTSEKELA ELRREIELRM LNSVKGGKTV
SNEVIGLSVK GPGLPRMVLV DLPGVISTVT TGMAADTKED ILKICKTYLE NPNAIILCIQ
DGSVDAERSN VTELVSSVDP AGKRTILVLT KVDLAEENLT NPDMIKKILQ GELFPMKALG
YFAVVTGKGN SGDSIDVIRN YEESFFAKSQ LFQGSILPPS QLTTKNMSLA VSKCFWKMVK
ESIGQQADSF KAVRFNLETE WKNRFPKLRD IDRDELYARA KTEILDELVQ LNATSTAEWE
TALREKLWET MSSYVFENIL ISAFVGDKPH AFNTTVDIKL KHWADTQLPR KCVDAGWAVL
REQFTRLNVS KKHQPEDGWS SCYKPLKEAV IEKALNSHTW NKRALESLRI IQQNALEDRT
VPSKACWKDA ILFMEDKIKL RLKELEKHSL HDSKTARWFR WSSPSEDELK IQAIADHLKP
LLHNISSRNP FIDSDEMIMI RRNVRNSGFE VGEDEVRETW HQLYRVWFLR KSLLTANECQ
SMFLHHQKGF DEVGDCSSVV LFWRVQRMLH ITANALRQQI VSTEVRYLEK EIKEILNEWS
HDSQMKRQYL QGAQVELAEK LKQVRVIQEK IEDFIAMLNN ESKRSAHVSG
//
