ID A0A0V0UX98_9BILA Unreviewed; 881 AA.
AC A0A0V0UX98;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|EMBL:KRX55379.1};
GN ORFNames=T09_5526 {ECO:0000313|EMBL:KRX55379.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX55379.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX55379.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX55379.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX55379.1}.
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DR EMBL; JYDN01000147; KRX55379.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0UX98; -.
DR STRING; 181606.A0A0V0UX98; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08834; ArfGap_ASAP; 1.
DR CDD; cd13251; PH_ASAP; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR043593; ASAP.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR037844; PH_ASAP.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45854:SF3; ARFGAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45854; ASAP FAMILY MEMBER; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 319..412
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 431..549
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 583..619
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 815..881
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 295..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 239..269
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 298..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 881 AA; 99473 MW; 749049439B07AAE8 CRC64;
MRDLKNKENF FRSFVSETED DLSSPTTSVF SNRVFRYRQA VQDFLENVAY DVEAISKLRK
GLKSFTVNQE LCMQCHENLA ESLCSLAALS NSCLATSDGN PEISTGWLRF SMMFKDLALL
NKVLVRSAKS CLIYPLAVIV KNDGRAKLSS KAVDKAFRDY QCKAAKLEKD AKSQTTSEGF
KLSQLDVAEA LLKERTILQY ELCQLFLKAS KMESKNSVGL VESMIELYYA LHTFFRRGIE
TLEELHEFVE ELEKKLDETK RSQNEDQKLL HNLSKSLKRS VVVLDYETAK TDESRDSTES
LSVTMLDSGP TEQPNSSTAL LKCGYLLKRS KRKMHRMWYK RRCEIRDGFL HIWHENEAQA
PIELNLLTCQ IQPSADDERC FIVQSSERKY EFQAESENSA NEWLNLLKKA KKQLEQEAMS
SEATSGERVE KVAMEKIKSL PGNDRCCDCT SSRDVSWLCT NLGSLHCIDC AGVHRELGVH
VSRIQSLNLD RLDRATALIP LALGNQKVNM VLEAGYSGLK MLENSVERKR FIQKKYVGRK
FVVPVTDRPM EYLIETVALG SVSNLLHLYA SGVDMNSIVD PDSNSTPLLM AVAADAGGSH
LAFIQFLLQN GADVNAQNCF GDTAVHLCIR QNKPECLKLL LLVWNVNVEL CNVDSLTPLL
LAQQLQHETC ERLLNKFEQN AKSTFADIEF PLSLLNEGAD DSAELVDVPL AMRFSTPRAS
QLFPTRSVLV NSDQRKSVLD YSANGSRNSV FGESGCLSST FSLPQKSFTL NRFDNSNISE
PTPANLATFS SFQRKPQCTT VLPRPAPRKK KPTSEIRKKC RAIYNCKADN SDEISFSRGD
LIFITREHLS DENDYWMEGY VADRPDIVGR FPTSYVTFEK E
//
