ID A0A0V0UYE1_9BILA Unreviewed; 2058 AA.
AC A0A0V0UYE1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Small ribosomal subunit protein eS7 {ECO:0000256|ARBA:ARBA00035279};
DE AltName: Full=40S ribosomal protein S7 {ECO:0000256|ARBA:ARBA00035404};
GN Name=dcr-1 {ECO:0000313|EMBL:KRX56226.1};
GN ORFNames=T09_5572 {ECO:0000313|EMBL:KRX56226.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX56226.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX56226.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX56226.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS7 family.
CC {ECO:0000256|ARBA:ARBA00007820}.
CC -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC {ECO:0000256|ARBA:ARBA00035116, ECO:0000256|PROSITE-ProRule:PRU00657}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX56226.1}.
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DR EMBL; JYDN01000127; KRX56226.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0031054; P:pre-miRNA processing; IEA:InterPro.
DR GO; GO:0030422; P:siRNA processing; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd18034; DEXHc_dicer; 1.
DR CDD; cd00593; RIBOc; 2.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.30.160.380; Dicer dimerisation domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 2.170.260.10; paz domain; 1.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 2.
DR InterPro; IPR038248; Dicer_dimer_sf.
DR InterPro; IPR005034; Dicer_dimerisation_dom.
DR InterPro; IPR044441; DICER_DSRM.
DR InterPro; IPR048512; Dicer_platform.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003100; PAZ_dom.
DR InterPro; IPR000554; Ribosomal_eS7.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR14950; DICER-RELATED; 1.
DR PANTHER; PTHR14950:SF37; ENDORIBONUCLEASE DICER; 1.
DR Pfam; PF03368; Dicer_dimer; 1.
DR Pfam; PF20932; Dicer_dsRBD; 1.
DR Pfam; PF20931; Dicer_platform; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02170; PAZ; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF00636; Ribonuclease_3; 2.
DR Pfam; PF01251; Ribosomal_S7e; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00358; DSRM; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00949; PAZ; 1.
DR SMART; SM00535; RIBOc; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 2.
DR PROSITE; PS51327; DICER_DSRBF; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50821; PAZ; 1.
DR PROSITE; PS00517; RNASE_3_1; 1.
DR PROSITE; PS50142; RNASE_3_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00657}.
FT DOMAIN 420..602
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 791..947
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 994..1090
FT /note="Dicer dsRNA-binding fold"
FT /evidence="ECO:0000259|PROSITE:PS51327"
FT DOMAIN 1254..1357
FT /note="PAZ"
FT /evidence="ECO:0000259|PROSITE:PS50821"
FT DOMAIN 1577..1738
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 1792..1960
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 1985..2051
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 88..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2058 AA; 234482 MW; 4A7E4BC1E6F31DB2 CRC64;
MGMAASSTNG DAMEDESEME AFDVVRIADD VIQRLRFGSQ DIFKSEDPVI DDMLIESAYR
IQYETLRQDL IATQEEVARL KRQLQERDYA ERKKRNSESH KSRKTFKRGE AEQLKLEQKL
KSTVQDVKTK FMQYSCHQLC MDKEMEVMKC FDLNRQKTLK CSKLKLSNEL VKLLLILEFM
FTNSAAFRKN NIDMVYGTLN NLVRASKDSV TELERQVSQV LYDLKHSQDL QYYVKEDLTF
VSAKEIDVGN RAVIIVFVPF PQYKQYRRIL VRLIHEVEKK FGGKHVVFVA KRRILPKPTR
GKRKITQKQK RPRSRTLAAV HDEYLNDIVF PAEIVGKRIR VRLDGSRLLK VHLDRNQKAA
VEHKTETFAA VYKHLTGKEV KFEFPVPLVC NNRLFIPAEW RKNKAVGWRT CDYIRLKKEL
LECAKKENVI VTLGTGTGKT FIAVMLIREM SESVHQPLKK GGKRSLFIVD KVPLVKQQAE
HIRINTNLKV GEFHGALGVD CWSAKIWMEF FDKFHVLVMT AEIFRNILAH GFIKFDIVNL
IVFDECHHAT KQHPYKKIME LYKLCYNNND SGIQPRILGL TASVMNKKGD EIGLQKAIRN
LETTLCSRVV GTSHAELLKL YSADPHIAIV ACKNDNKYDW HELDLFFQHL VRSTQKSLER
CGRDCEGNVS LYIQHVCDVL AKLDSIMGQL GPWCALQVCK QMLQSTTNLA TRISTLLADD
EDNNLFSLLT SASDAGSSVW LGVLKTCLKV TSVKLKRHIG LVDSVQKLKC VVSDRLSALL
NILDSENGSS FVNDLLTSSS KPFGIVFVNQ RLVAYCIAIL IDTAKKLQPR SFSYLEVDYV
VGSRMSAEIV EPSYARQEEV LKNFRHGKLN LLVATSILEE GIDVRHCNYV IRFDTPLTFR
SFVQSKGRAR QKIAYYTILV QDRFLESFQE MLNSFVETEK FLKSYSGNND QVDNCRKEVN
LPNGDVDSLV EPYYTYFEEN GTVKKAACLV LSSAHNVIKR YCNKLRKDRF ADSSPKFSVQ
TILNKDLSIS YVATVQLPTT SPLKKKIEGK PMQNAKLAEM AAAFETAKML HAMSELNEFL
VPPVTVRKEI ELKEDEQFFS ISSRSYYLKE VPDALYKAIP RADQKSYLYA ISISSIESFL
PRLGILVSKP IGNLPGFSIF TDESYIDVEI EFVEETSYSA HQLDILTSFH CCLFKNYLFS
GETDFIFDPE NAACSYLIVP LKCEYNSKCS VDLSIAEKII NWSKDVSHIP QQRIVYPWYK
NKGDRDFYYF VTAVDNTCTP MSPFPFKMYR SFAEYFEVAK QVKVLDKNQP LLNVKMVSFK
RLNLLCEKQI SILLFDFDDD TSSCQCKVVP ELVVIHPMPA SMWRCLIFLP TVLYRMNHLL
IAEQLRLQIL REAMFPGEVL EENCEIQPLN KDWYLLASRL NDMCIVDNQL PVKLSKLQVN
SNSAAAATAT GSIDPETQAL LEEFDVRFCN ACPTVPVDDQ LDILTGNSVA ESHTAESNDE
CLFDTHFSLQ LLSSIQPQQQ PLENVDFGIV ESDGESDFVA APALPESELN LFVEPSDVSD
TPAQHWPGPQ CRDVLRALTL RNAQDMFDLE SMEALGDSFL KFIVSLHIFK KETSWNEGRL
SSLRSEIVSN TNLFNLGKKK LLQAKLTAVP FDPTAHWLPP CFRSLAALES GYESVNELID
EGDSKKKNQA LKAKTPAPVV VAECYEMCSL NRTHQVICDK SIADCVEALV GCYLLEAGMR
PAIKLLKWFG IDIDDNLMNL LSSSSSSAFF SENCVLIGPE AKIHSIWTAY DLNSFEAKIG
YRFTNKAYLI QALTHSSYNE VETPVTDSYE RLEFLGDAIL DYLISRHLYS SKRIRSPGLL
SDLRSALVNN VFFASMAVLN HFQKYFLYFN AELLTVNERF VLTMRGLKES VNFHNELYMM
EEEQDDDEKE TGEFAEHVEV PKPLGDIFES VAGAIFLDSH CSLATVWQVY YNMLAEEIDK
CLCHPPISPV RHLLELEPER VQFNILDREE GNISVRVQVV VTGKGSFIGS GKSYRIAKHA
AAKKALRELY PTSNHFII
//
