ID A0A0V0V0H9_9BILA Unreviewed; 1475 AA.
AC A0A0V0V0H9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Ribonuclease 3 {ECO:0000313|EMBL:KRX57033.1};
DE Flags: Fragment;
GN ORFNames=T09_6332 {ECO:0000313|EMBL:KRX57033.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX57033.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX57033.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX57033.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the dynein light intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00006831}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX57033.1}.
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DR EMBL; JYDN01000110; KRX57033.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd00882; Ras_like_GTPase; 1.
DR CDD; cd00593; RIBOc; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 2.
DR InterPro; IPR008467; Dynein1_light_intermed_chain.
DR InterPro; IPR022780; Dynein_light_int_chain.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR12688; DYNEIN LIGHT INTERMEDIATE CHAIN; 1.
DR PANTHER; PTHR12688:SF0; DYNEIN LIGHT INTERMEDIATE CHAIN; 1.
DR Pfam; PF05783; DLIC; 2.
DR Pfam; PF14622; Ribonucleas_3_3; 1.
DR Pfam; PF00636; Ribonuclease_3; 1.
DR SMART; SM00535; RIBOc; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 2.
DR PROSITE; PS00517; RNASE_3_1; 2.
DR PROSITE; PS50142; RNASE_3_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 551..731
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT DOMAIN 785..913
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1314..1380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1429..1461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1314..1379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1445..1459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1475
FT /evidence="ECO:0000313|EMBL:KRX57033.1"
SQ SEQUENCE 1475 AA; 167261 MW; 11FA782B69E87A3D CRC64;
MKSTRCVREE LSVPQSKESD SMDQNPSSSF EEPLLVGLND FIDQDFDIDD EEQEEEEVTI
FSQSSPRLTV SCVSAHDYYK TIACVQSDVK VATQKLTALH CEFDQHVVQL FRSAKQTWQK
DENDGASQSP VKLQCSAESD EQDEEHACEG GKQPNGNVNG DSHNNYDVND NGRFKDALKE
LERKRRHPAR LHPDIWYNDA GQLNDGPSCR CCWRARQKGI SHGRYPGEAR VEPCDPLSNN
ANRLHYYRVV IKPQANLFQK FSITEIEYKD KLYSFDGFGI LSHEPIDRNM PLCRLNRWNI
DYEVSLVEEV VPDFFSVRDL DLFWEYVFVE LLELYDVKLF AANVEDGCPI FHIYPRFVCK
RKEKTGCTQQ MLPMSVVLEH LLQNCRLIFD QPAERGDFND RINKQHLDKF SERLKGQVVA
NPWKRPVALR LDQLDRMQKA PDGYSVIVHF GRHPTVTTYA GTPEYQRAWK RFAKFRRVVM
LQLYPRTEDR AKLAKMEAHL TELKAKNSVK RDLIMEVSCQ DFMQTGIWSD VVQHCLILLV
LLNHIRFHRC LRVFQQRIDY SFRKPSLLEL AFTHPSYRAD SGTNADHVRN VLNNCGLRQL
EFGSKRTNPW NSRKRGVSCL VDVMSRMGEK KSRASSTVNN ERLEYLGDAV IEFLTTIHLF
YIFPDLEEGA LAPYRTLMVQ NSHLSKLAAK MGLDEFMLFA HGPDLCFEED MRHAMANAFE
AILGAVYLDG GVHVADRVFG RFLFPPDWNK ALHWVWFHPP RHPLQQEYPD GDRHLIHQCP
TLQKLTEFEQ RIGVRFNHIR LLARAFTRKC VGYNFLTLGH NQRLEFLGDS VLQLVTTEYL
YKHFPDHQEG HLSLLRSSLV NNRTQAVICD DLEIPNFILQ PPAFLRNEPQ ELRMKDKADL
VEAFLGALFV DHSLDYCAAF VRYCFLPRLK QFIEEQRWCD PKSQLQQCCL ALRNPSGAQS
TVKEEIWSKI LCETQSRSKC ALPTASVIVL GDSDSGKTSM VARLQGVEEP KKGAGFEYHY
LEINPDYKVG SYAYQLSSSL PDISAGDVPR LGVWVLDGDP LYAPLLRFAL PAENLKHSVA
LICCSMAEPW NIGQSLQRWT DVLEKHLNQS GLYSTHVLSE CRERQVRFWQ EYVEPLDSSS
HSELGQKVPS MEPDQILLPL GQSTLTRNLG LPLIVVVTKC DLLSSYEKQF DLKDEDCDLI
QKQIRQFCLK HGAALVYTNV KEGRNCDLLY KYILHRVFGF PFTQPACVID KEAMFIPAGW
DNEKKISIIE DGLPEGAEEA FLNRFSDQLV NPLNNSFNDN NITATRLQTL LNTTLPNTQS
PGQHRPDGSS PMPMSITSPR HSSDKSRPSP IGGQSSNGLF SSASVSAGGS ATSAQSKKAD
SIGKIAMQTV SGTGTGAGAA GSVGGGPVGP SSEGALAQFF NNLLVKRPAS ASTAAGSAKL
TSESSIRERT FDDSESETQT DWHYCCSDDA SKAKR
//
