ID A0A0V0V9L8_9BILA Unreviewed; 1285 AA.
AC A0A0V0V9L8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Neurogenic locus notch-like protein 1 {ECO:0000313|EMBL:KRX60217.1};
GN ORFNames=T09_8675 {ECO:0000313|EMBL:KRX60217.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX60217.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX60217.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX60217.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX60217.1}.
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DR EMBL; JYDN01000062; KRX60217.1; -; Genomic_DNA.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 5.
DR CDD; cd01767; UBX; 1.
DR CDD; cd22249; UDM1_RNF168_RNF169-like; 1.
DR Gene3D; 3.30.70.3310; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.10.25.10; Laminin; 7.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR010660; Notch_NOD_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR001012; UBX_dom.
DR PANTHER; PTHR24044:SF511; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24044; NOTCH LIGAND FAMILY MEMBER; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF12661; hEGF; 2.
DR Pfam; PF06816; NOD; 1.
DR Pfam; PF00789; UBX; 1.
DR PRINTS; PR01983; NOTCH.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM00166; UBX; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 6.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 7.
DR PROSITE; PS50033; UBX; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 848..870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 226..302
FT /note="UBX"
FT /evidence="ECO:0000259|PROSITE:PS50033"
FT DOMAIN 305..342
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 343..384
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 387..423
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 424..461
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 576..612
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 614..650
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 652..688
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 1125..1157
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1158..1190
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 197..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 332..341
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 374..383
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 391..401
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 413..422
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 451..460
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 602..611
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 640..649
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 678..687
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1285 AA; 143602 MW; A525326F19365844 CRC64;
MEDNDNSTLA EMGFPQHHID LARQITGSSD IQVLCDWLMA NSLTLDEADK GETAVEQKLL
EEMKSIEDRH QVGDLEKMDL KQAKTEAPLE NQPEKKVTYM KCNDCGRLLS SQKAMKQHSL
YIRMQEMAKQ REEKEQRKEI EAEKERRKMG LEMADYRRRL ELEEIKQMVK QRKQQKHDDY
LAKKKILDEI RMDREARQLQ KSKAASASEP SASSSVGEEE KASIGNDLET CTLQFRMRNG
SKVVKEFKKT QTWADAKLFA DNFFGSERLE YFTTFPTRFF NEEDKSKTLL DMKLHPSAVI
HVRSLNQKCE LNLCKNGGYC FLNEHGNAQC ECTPGYVGKH CQTVDICMSN PCKNGGSCVY
QIEEDEIVSF TCLCPLGLTS TFCENPLPNA CDSLPCKNGI CELETLDSFH CRCESGYEGK
FCENFTRCKY NLCNNGGQCM VLPDGTYRCV CPKGFAGSTC ESDIDECTRD ICEHGKCTNL
FGDYQLSISI DVPVYFDSIV LLGVLAVHAS RALVGKIVIK CNVRAVRFCA TTTATASKLL
QTTIAFVSQS TNYPPTLSSS SSSSLLGFTG VHCEVEHFNC QQTVCENGGI CVIANGTSKC
LCTEPYTGAT CGTGIGSCFY NPCYNGGVCH EFNDHFTCAC PAGITGKYCE ITSNRCSANM
CLNGGTCFNY NDTFFCSCPD GIFGRRCQFY EAGVEQVEYE DIVIVVLVEP RTFMSTLSEL
LAIINSHMHI NITLKKDELS LPKVYSWNSQ SGYDKNSNAV LFNNTDETGN NNWKFLIANQ
ADAIYGTLAV MTISSSACTR ENSKSCVAKF GEVINQLASD AQFDYLKSRV SWKINTVDRK
KKSEISNFLP LIVTVISSLV LIIFFVLLML QRKRLHAATW HPPVEEGPVN LNTTLRSNYL
TPLASVLQKS TTDKKATNGA QKIFLKSKQD SFCATDSQTV DQEKRYATSR DTYKWSDLHL
CIIHGVLVDP ETITDDQVNA LGPDDQTPLM VAAERCTSDV ELQFMIMLLN AGAKMEAQTE
LLKETALIIA IRHSRLQAVL ALINFRCSLE TADVDGNTAL HHAVMTRNTE ILCALLDSEL
CNTETRNNDG LTPFVLNAKV CGAVDTEIAF LLLSSGASID STDDEGMHAV HYAAINGNIP
LLELLFQRYT NINLMDCYGR TALFFAVREK HTEAVEWLLQ VGGTMLEMHD QKMTPMSVCI
PIDDGHYATI TFPSAPDGET FQFPAVQLDD FPNISDSPKD ACCTDLTEEQ SYQFPHSTSH
FETLHTDTTE TFIPTQQQYW SWCFS
//
