ID A0A0V0VP32_9BILA Unreviewed; 735 AA.
AC A0A0V0VP32;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Cyclic nucleotide-gated cation channel alpha-3 {ECO:0000313|EMBL:KRX65288.1};
GN ORFNames=T09_13047 {ECO:0000313|EMBL:KRX65288.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX65288.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX65288.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX65288.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX65288.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDN01000018; KRX65288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0VP32; -.
DR STRING; 181606.A0A0V0VP32; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01463; EAGCHANLFMLY.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 528..634
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 735 AA; 84099 MW; AE4634422F191764 CRC64;
MFDEKKKEQL RMVLTNAQDP RLISEEGEGV VELRCGLRDD IDDNVNPSST TITFDGQSTQ
LELEKRRKLK TKTKMTTLMT KSRNLHDEDG RSGGGWSLSK AAFRSRERAE ESSPAASKRC
HVARLLVKAV SSTQSQSDCD LDGKTKPGDD NAKRNLSTDI RRLCSKIAYD PVNPSDGWYK
IWLGVVALAY LYNMVVVVAR VSFFARFAHQ YADSVWPFVV DYITDVVYIF DVYVQMRQVY
LEQGCVVLDR NRLFRHNASA NGGRNLTRCI ASVAPADHLL TLVFGQSALV SASRFNRLLR
SYRLVEFVDM TETETRFPNL FRAIQLAVIV YLIFHWAACF YYLMSLAYGL ELDSWVYNSE
RMLDPVIDCP RPTCGSRPAP RTSTPCQKIT YPELLKHYLL SFYWAALVLT SVGEQPFPIE
LGQYVFTVCN IIAGTLIVAA LIGNVRIVVI SMNMHRSQFL NRLDGVKRYM ELHKVQPPLR
GRILNWFNYL WDQKQATDEA AVMELLPLNL RTEMAIALHM RTLRKARVFK DCDPGLLAEM
VLKLRMEIFS PGDYVFRRGD VGKHMYIVKR GVVNVVAEDG VTVFVSLNEG SVFGELSILD
IPGNKNENKR TASVRCVGFA ELFVLTKNDL LECLDKYPDA HKHLLDKGKE ILRKDRLLIE
TDVVEHEAFS NDNFEQQQFE NESVDELNKE MQRLWRRLQF IDRAVKKECD KTEQRVTTLE
RQLLGNIHPC NSTTP
//
