ID A0A0V0VP67_9BILA Unreviewed; 2014 AA.
AC A0A0V0VP67;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Pappalysin-1 {ECO:0000313|EMBL:KRX65284.1};
GN ORFNames=T09_282 {ECO:0000313|EMBL:KRX65284.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX65284.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX65284.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX65284.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX65284.1}.
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DR EMBL; JYDN01000018; KRX65284.1; -; Genomic_DNA.
DR STRING; 181606.A0A0V0VP67; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR CDD; cd00033; CCP; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR000800; Notch_dom.
DR InterPro; IPR043543; PAPPA/PAPPA2.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR46130; LAMGL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46130:SF3; SUSHI DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF00066; Notch; 1.
DR SMART; SM00032; CCP; 4.
DR SMART; SM00560; LamGL; 1.
DR SMART; SM00004; NL; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1475..1533
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2014 AA; 225317 MW; C584163CEE3306D0 CRC64;
MFFSAKDVVS SEEEEDDDDD EFCSRGEKKK NLGNLCSCCG LFVICIRLEV KDGSLVVDQV
SRFRDEGSSS CILTDRLDFI RSQERKLVLF LERWATGDWK RERSAAVESD VSNLNTSNGP
LDSGWVWGMR RRLYIKGSNL SSRFDSRNYK KQSRRRVCRF LVFSSSALAA SASICSYSYS
YFAAAAAATT TTTTTTTTTT TATTYSSFAY SSFVFCVSAM HHLLLLFTLC LACLTNAVDD
TTLANCAVGT GTRLDHRYHP NVRHPRSVSN GGGYSTTAKA IYFDGQERTV RLQDVGQLPR
DQFTLTVWTR PEGGQGDPAI IAELADGCSG DDDDDDGPPF VWQLGIATKT ASREKGAHFF
FQMRNEMSSS ATVLWSHYPY KAERWVHLAV TYDGIMLRFF VGGALVATTD KQIGPLFSNI
KSACKHLLLG GPMPGRFDEG HTMNFRGAVD ELQLWSTFQE YDFIQKMATG RNAQEAVNNN
NHNAQHPTTT SVLIINAQSV AKWKPAGDFA PKFVPSDLDA FFNTYQLLVH ACGQTVCDHP
DVVRSYSANW ELRQSKVVRY KVADDVINIV DNSTGKGIVS DRKIELQHGS LSGAFAKYNI
TWQMEIVKIA NANLRKKKII FGCDSSKIGN KQCDLECRHP ITGNDGGDCD ELMLVRCQRR
MLGNGRCDPE CNFPEYSWDQ GECCNKTLTD VTTNCIDPQS PFRPYIGIEE YKRMLNVSNE
DALTISFVEW SNGDLIGLST FPWEKHVFSI YGGIVVQPKR FGSDGHRNNL IHEFGHALGL
WHVHHGISEM TCDDPCRETK PSLYTGDLCE DTNPTPKNVE CKDPEYVSFD SRQSMAELSG
CESGSQMYLN TPYDNYMSYS DGECATHFTP QQVARMHCYL DLKYSSWMAS SESLREYVPT
APRILRKTET SLTFAWLPPL SWHQCKPAVE RCQHCECDTD GRFIQYASRV IANHTARTTS
YWSPDQALGP PDAEPCEAST KSWLPDAQNC DNNNACSLVL GFEVAVVPAH LKLWISWNAA
DGLKHFILHF DDSSMIALPP ATAFCDMPYT LSLDTDKRLT KVELTTSSPF VSIDAVQIVS
NPNHELCSKC SHIDYNIVRE PPFPKPPLVQ STADTFFTDR DLKQDQVYMY RIGARRTNSN
GAVYFSPPLI YSHSWSFCGD GNLDEIAYVF VLARLCSLVW RSPSFCYSLD GVQHAHAING
SPIMMSDMPD VSYASEHSDQ WAARAFSNAE PINLRCNTTM ILGPPRNLVC QVNSPPGLSW
QPCLPSVMKN VWIEVEFEQP VVATAVFVHL ASDGYAGVDS EYRFLRLELV SVDNKYYELQ
NSKLVTVSCA KSPLEYPVWH DLTKPFFYSR AVRIHLSSER ISIAAVRLRS KRNFDPVVLE
LCSKSDMLYS VFANQCVSSQ CSVVSCKSVI VNHADVQCTG HSNGDSCIVT CMKGYHLVKH
ERAQTHAFSY SSQRSAKIIC LNGQWSVGNL KCEPVDCGWP KIFRAEVLCP DGTRLGAKCS
FRCLRPAIMQ GTKREITCGE RGAWSVPEAY CQLSCGPSLE GELNGRAVSK LCRINFLTLD
LKSVGYPVGT KCRIVCKAGY HVEGHSINNS QSYLNEAVNL NVSGYYSINQ QAGRVFKRVC
DRNGHWKGHR CVKIKCPEPA VVYRGLYNCT KGFEVGSQCS FYCPFSSQIR DSVCMMDGTW
SIADPCVLPK DVTCSIPHAP GHIVVSCPSK RLVGSTCHVA CDAQGYDPVV EHVVNSDRNF
KMHVLQKITK LTCSIRRKWE PEVESLICVK RCTQDFVGDG WCDFQNNRAY CGWDGGDCCA
STAKGGKVKL MFPLLCTSHL CRCLDPYAVE NRNPRIVPRA FLVQGYHGGE ALDKEEEEED
LDENNSTEHI QSPDLMMMLM NNDKNRTNPS WKPLGLGSRV KFAWETSGGG FSTAKLDHLS
SSMLVLFLQA LKNVSSDPRD PFLLLQNSAT TNATIKRLKE LDAMTRFLKR PTASTAQPLT
WTTRWFRRRV VHPQLSTSIL KALRKQHESL QVKS
//
