ID A0A0V0VWS8_9BILA Unreviewed; 538 AA.
AC A0A0V0VWS8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
DE Flags: Fragment;
GN Name=pak-1 {ECO:0000313|EMBL:KRX67964.1};
GN ORFNames=T09_8599 {ECO:0000313|EMBL:KRX67964.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX67964.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX67964.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX67964.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX67964.1}.
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DR EMBL; JYDN01000003; KRX67964.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0VWS8; -.
DR STRING; 181606.A0A0V0VWS8; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01093; CRIB_PAK_like; 1.
DR Gene3D; 3.90.810.10; CRIB domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR033923; PAK_BD.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48015; SERINE/THREONINE-PROTEIN KINASE TAO; 1.
DR PANTHER; PTHR48015:SF35; SERINE_THREONINE-PROTEIN KINASE PAK; 1.
DR Pfam; PF00786; PBD; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PIRSF; PIRSF000654; Integrin-linked_kinase; 2.
DR SMART; SM00285; PBD; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50108; CRIB; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:KRX67964.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transferase {ECO:0000313|EMBL:KRX67964.1}.
FT DOMAIN 81..94
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT DOMAIN 259..510
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 7..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 288
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX67964.1"
SQ SEQUENCE 538 AA; 61038 MW; D0FB4327B2DCF528 CRC64;
LLFIMLEEFD FDDRPPPPPI RLASNAPKDP QQTFLDLKPL PREPDAEEQS SHGKQKRDKK
EKSKGFRKTK KDDRQNEKPI ISPPSNFEHT VHVGYDAQTG EFTGMPEQWK LLLQQSMITK
SEQQRNPQAV LDALNYFTTD GKAAKQKFLQ LKPLISHVLP NTQLSYCQSQ AFPPQYSPPP
PPDDDDDLPP VIPDRPTRTM SVYTKPIEEG SLPAPVQLNG MMGVNVAQFR QQKKKRMTDE
EVIERLRLIV SIGNPQRKYT RLEKIGSGAS GHVFTAIEVS TGAEVAIKQM NLAQQPKKEL
IINEILVMRE NKHPNIVNYL DSYLVGEELW VMMEYLAGGS LTDVVTECQM EEGQIAAVCR
EVLQALEFLH SRGVIHRDIK SDNILLGMNG AVKLTDFGFC AQISPEQNKR TTMVGTPYWM
APEVVTRKQY GPKVDVWSLG VMAIEMVEGE PPYLNENPLR AIYLIATNGK PDFQSREQLS
SEFQEFIDFC LEVEVDKRWS SSALLRHRFL KCAKPLASLY HLIVAAKQSI AKQQQQQQ
//
