ID A0A0V0WKE7_9BILA Unreviewed; 1139 AA.
AC A0A0V0WKE7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Protein transport protein Sec24C {ECO:0000313|EMBL:KRX76299.1};
GN Name=SEC24C {ECO:0000313|EMBL:KRX76299.1};
GN ORFNames=T06_360 {ECO:0000313|EMBL:KRX76299.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX76299.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX76299.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX76299.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX76299.1}.
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DR EMBL; JYDK01000104; KRX76299.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0WKE7; -.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF4; SECRETORY 24CD, ISOFORM C; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 471..509
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 548..789
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 797..878
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 890..991
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 1009..1067
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 233..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..258
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1139 AA; 126344 MW; 32A7089BACFEF1FF CRC64;
MKRQVPCSIK YCTGRKFCSI LELRNTMAFN PPPPSIYSSN MHIPPDVPVF SGSNVSLQNG
MNGSLPNDGN QALNYSRNDY SSNEQSAFTV QQATADFQRM KLNVDSTFSS TQQHPPPPIP
TVVSPNVGYP SNFNYDGTTA TASFLSAPMV SVLPPQPDAS AAPPVMNSAA TGPSSQMLRS
GFPSNFANYG PPSAGFAPPA ANHPSTPIMH PVNVIPEDRP PLVFHGANMP LAAQSNNSAS
SIPPPPMSSQ PSSMPPMCPT DFPSMQRLPM RQSTTTLPPP PQSSGFSGVP TQSPFSPPSD
FSKNAVPGAP PTGCSMNQYP PMPSAPIPGQ NFSHGTSSPF PPTDGQTGAY LPGGLPPQPQ
MPANSQPKRL DPNLMPSAIQ VFEDDRKTKA GLFQTGVDHA ELPPLCTTEF YAEDQGNSNP
KFIRSTMYSV PVSNDLLKNS ALPLAFCVTP LAKLCPEENP LPVVNFGDLG PVRCHRCKAY
MCPFMVFFDG GRRFRCPFCN TSTDVANEYF SHLDHASRRI DMMERPELHL GSYEFVATKE
YCKDQLFPNP PAYVFVLDVS YNAIRNGLVN TFCQNIKLLL QNLPKEHGKD CMIEVAFITY
DQGVHFYDLK NGSGSPKMMV VNDVQEMFVP MGKGLFVKPS VASQAIDQLM EQIWSLFGEN
RITEVILGPA LQAGVEALKA HNRSGKIFLF HTALPTFEAP GKLKNREDRR LLGTDKEKTI
LTSQSDFYAK LSEECRSVGC GVDLFLFPNS FIDVATVGEI CRLTGSQMYK YPYFEANKDG
DRFLADLRHA IERPVVFDAI MRLRTSTGLR PVEFYGNIAM NNRTDIEMAT VDSDKCVTIE
VKHDDKLEGG NAYFQVAVLF TSVSGERRLR IHNLALSVAM DYAAMYRSAD VLTILNYLAK
FAERHQMQKT PKEVRESLTS RVAQILATYR QYCSPNSSLG QLVLPELLKI LPLLVNSLLK
SDAFSGGSEL TVDDRAWLMQ LLPSMSPLDS VLYFYPRLTP LVRLELLNES PPAVRCSYEN
LLHDEAYLLD NGVLMFLWIG QSVPTQWIQD VFGVPTFAQI NTDKNQLIEK DNPTSRSLRC
WIEELQAGRQ RRAKIYIIKQ GEKLEPWMKK FLVEDRNDNC PSYVDYLCYI HKEIRSYIS
//
