ID A0A0V0X061_9BILA Unreviewed; 1571 AA.
AC A0A0V0X061;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=PAX-interacting protein 1 {ECO:0000313|EMBL:KRX81420.1};
GN Name=Paxip1 {ECO:0000313|EMBL:KRX81420.1};
GN ORFNames=T06_879 {ECO:0000313|EMBL:KRX81420.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX81420.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX81420.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX81420.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX81420.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYDK01000031; KRX81420.1; -; Genomic_DNA.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0000931; C:gamma-tubulin ring complex; IEA:InterPro.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008962; F:phosphatidylglycerophosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0033566; P:gamma-tubulin complex localization; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd17710; BRCT_PAXIP1_rpt2; 1.
DR CDD; cd17711; BRCT_PAXIP1_rpt3; 1.
DR CDD; cd14524; PTPMT1; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 6.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR022214; MZT1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR044596; PTPMT1-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR23196:SF1; MEDIATOR OF DNA DAMAGE CHECKPOINT PROTEIN 1; 1.
DR PANTHER; PTHR23196; PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN; 1.
DR Pfam; PF00533; BRCT; 2.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF00782; DSPc; 1.
DR Pfam; PF12554; MOZART1; 1.
DR Pfam; PF12738; PTCB-BRCT; 2.
DR Pfam; PF16770; RTT107_BRCT_5; 1.
DR SMART; SM00292; BRCT; 6.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF52113; BRCT domain; 5.
DR PROSITE; PS50172; BRCT; 5.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000054673}.
FT DOMAIN 31..183
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 104..172
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT DOMAIN 176..252
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 271..360
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 996..1082
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 1094..1167
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 1277..1358
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 504..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 835..904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 942..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 666..710
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 854..902
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1571 AA; 179643 MW; 9A57A5E4BD1C874A CRC64;
MAMGLLSWAT FYSTLSYNLL RNRLSETDWP WYSKIDETVI LGALPFKSMM NELIDKEHIG
GVVCLTEPHE IEHRWAAAKD DWEARGVSYF WLPIRDFWYS TSLENVREAV KFIEECEQSG
KKVYVHCKAG RSRSAMIVMC YLMQKHGWYS TAAHALLKSK RPRIVLWHDH WLTIEQYAKT
FQLKVYLVPR TVEESRAEKV RKILTENGAR LSSYLTDSVS ILIADHPDSS EVGEARDIYD
IPVVASSWVF ASAWCRCILP YGAPGRLFSP EQKQIFRDCV FCPTQMSRHD ANILWSIIVS
LGGECERVLT SRTTHLISFL ISGNKYRIAS VNDSIRIVIP QWVVDCAEAG ELLSVEQYHP
SNFVQENSAD ENDMKAEQEI QNLAATLKME AQQLVERNQT NQYHMSPYSA PYGPPTPVCE
TVGPTNPMHH VAMHQQQQHA GMNVSSPAPG VSPACGFNPS VDRCYQLSPE MGANSPYQQM
GPRISPQQRF WYSNNVQPPF PVQHQTQMHG SPQQMQMIRP QQMPVSRRQS DTPLMSPSGN
GSPLGSPNPT FISHSQQQYS ASPMQAQSVI YHSLANEQYQ SPPQQQQQQQ PRQQQLYSHQ
QQNSFGGGYQ HEMQLVGAPQ RQVYMPQQNQ LHQNHGQLIQ QQQPRFSDST PPNYSSAAEY
AGNAAVQLQQ AKKMSLQQQQ ESLKQQQMQY QQQQQQQQQQ QQQQHQIQQQ QQHQIQQHQI
QQQHQVQQMQ QQKQQQMQQP QQQQQQQQQP QQIQQVQHQQ QLSASPRVQF QHHHFPATPI
DASLHRQQFV PTTRINQGSF PNSNQIQMQA HCQLRHGFQR VSYPGYALPL QTSTPATISL
PSGQRPTVPS YPVRDFNPQM QPQQQLQQQQ QQQKQQPQQQ QPQQLHSLSN QQQYQASAPQ
QGEMGLHQKE PRLVPPSLQQ PYQVMQVAGS QIPNERFQSR NFQQPYSPRM GTTSLKESRS
VRPLTQALPL SSSVESVKTQ PPAMQFFGHD PRVDVPPELC LVGCVFLIVD YERTLDQKEV
SDWRIVINLH GGDVEIMYST KCTHVVCESL RHPVVQQALR DNKRCVTAQW LNDVIMNKKL
LPPWKAIHFP SFFGDNKPCK GKIVAVSGFP VKERSCLKQM ILAIGAHYTA YFSRHNHLLV
AKTYCGPKVM KAAEWKIPVV NLQWLTEVFF GQTTALQNIN NAKYHQFVPK ELSLQPNFDP
FRIDTATAMP MLMNAWRNPV LLDMEICRNA SKKRFQIEND DGKIFPHKRI KLSPPPADAD
IQKRCAELAK CGKNVAEVRI CFTGLYQAEV NHLEKKVLWL GGKVVQLVSE CTHLITADLK
RTRKLLEGIS LGRYIVSPIW IRQSYKQQQF VDPVDFIVKD EGNEKFFGFN VKLSIWRARQ
KKLFEKLLFY VTPSVQPFPS VLGDLISTAG GSLIRQCPSS RMMLQLKDIG TQFVVIACDN
DLHICQALLD AGVDIHSAEF ILTGILRQEV DFQSYKLEVR PVEQQPRAFN LLIEEQRSDC
YVGKCSKKHL PQNPLFVIDD ADLGGLHRIA KLLKVDLDRE SLAICVRLIE AGVDPERLAI
VFCEISNLSR S
//
