ID A0A0V0X4I0_9BILA Unreviewed; 536 AA.
AC A0A0V0X4I0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=TWiK family of potassium channels protein 7 {ECO:0000313|EMBL:KRX82836.1};
DE Flags: Fragment;
GN Name=twk-7 {ECO:0000313|EMBL:KRX82836.1};
GN ORFNames=T06_5677 {ECO:0000313|EMBL:KRX82836.1};
OS Trichinella sp. T6.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=92179 {ECO:0000313|EMBL:KRX82836.1, ECO:0000313|Proteomes:UP000054673};
RN [1] {ECO:0000313|EMBL:KRX82836.1, ECO:0000313|Proteomes:UP000054673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS34 {ECO:0000313|EMBL:KRX82836.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX82836.1}.
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DR EMBL; JYDK01000018; KRX82836.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0X4I0; -.
DR STRING; 92179.A0A0V0X4I0; -.
DR Proteomes; UP000054673; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR PANTHER; PTHR11003:SF98; TWIK FAMILY OF POTASSIUM CHANNELS; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857, ECO:0000313|EMBL:KRX82836.1};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054673};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 60..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 160..218
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 283..352
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX82836.1"
SQ SEQUENCE 536 AA; 60166 MW; FE84202E13EDED27 CRC64;
LKSAVVMLSK SGAMLKSHAY QDQSRSNEEG QSLIGMEMNP VDEDDDVSCG KRCGRILKIA
LPHVGLVALL TIYTVCGGGI FHLIELSHEL QVRSNSLKLI SQTKTRFLEN MWNLSQAEGM
TSEQWQMQAM DSIKTLEIVL YEAYEEQYIT INDILNKTHR TIWTFPQAIF FATTVITTIG
YGNMVPKTVS GRVLCIVFGI FGIPLLLITI ADIGKFLSDL ITFLYRQFRT LKAKLGKHSR
NFTFCGKKIS INEDAKHSEL DNISEQTSES GDVHLPVVMA MVVLISYTAF GGLLFQMLEG
WGYFEAFYFC FITMATIGFG DIVPSEQVYL FFTIIYIVVG LALTTMCIDL AGSEYITKLH
YFGQKIETAR DAFGGAVVSG LHAGEQIFKH SAFIRTAGGR LIQISDAMLL NTKQATALRQ
KYGLPDDYDF SVVSSPLITD DGTLITNNML FAPVSPEVLK VAKTHIKIRP EEIRESDAFV
LQNRTFNRPF DGGLYKRGSV RSSRSLGKRS RKRQWLKQDK YKFFLIAPFI LKESCV
//
